Detalhe da pesquisa
1.
P-glycoprotein mediates the collateral sensitivity of multidrug resistant cells to steroid hormones.
Biochem Biophys Res Commun
; 447(4): 574-9, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747077
2.
Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.
Cell Rep
; 42(11): 113371, 2023 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938972
3.
Cdkn1a transcript variant 2 is a marker of aging and cellular senescence.
Aging (Albany NY)
; 13(10): 13380-13392, 2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34035185
4.
p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Science
; 374(6567): eabb3420, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709885
5.
Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis.
Sci Rep
; 10(1): 10868, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32616761
6.
P-glycoprotein (ABCB1) modulates collateral sensitivity of a multidrug resistant cell line to verapamil.
Arch Biochem Biophys
; 491(1-2): 53-60, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19772851
7.
Oxidation resistance 1 is a novel senolytic target.
Aging Cell
; 17(4): e12780, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29766639
8.
Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress.
Biochem Pharmacol
; 73(11): 1727-37, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17359940
9.
Senescent cells: an emerging target for diseases of ageing.
Nat Rev Drug Discov
; 16(10): 718-735, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729727
10.
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.
Nat Med
; 23(6): 775-781, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28436958
11.
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Nat Med
; 22(1): 78-83, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26657143
12.
Author Correction: MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Nat Cell Biol
; 23(5): 564-565, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33824512
13.
Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions.
Curr Top Med Chem
; 15(21): 2139-51, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26059360
14.
Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing.
Nat Commun
; 6: 6790, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25858675
15.
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Nat Cell Biol
; 17(8): 1049-61, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26147250
16.
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Dev Cell
; 31(6): 722-33, 2014 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25499914
17.
A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
Elife
; 2: e00762, 2013 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898399
18.
Epithelial-mesenchymal transition induced by senescent fibroblasts.
Cancer Microenviron
; 5(1): 39-44, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21706180
19.
Lamin B1 loss is a senescence-associated biomarker.
Mol Biol Cell
; 23(11): 2066-75, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496421
20.
Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.
Aging Cell
; 11(4): 569-78, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22404905