Detalhe da pesquisa
1.
Complex In Vitro Model Characterization for Context of Use in Toxicologic Pathology: Use Cases by Collaborative Teams of Biologists, Bioengineers, and Pathologists.
Toxicol Pathol
; : 1926233241253811, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38888280
2.
Common and Not-So-Common Pathologic Findings of the Gastrointestinal Tract of Rhesus and Cynomolgus Macaques.
Toxicol Pathol
; 50(5): 638-659, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35363082
3.
Spontaneous Findings in the Reproductive System of Sexually Mature Male Cynomolgus Macaques.
Toxicol Pathol
; 50(5): 660-678, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285336
4.
Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Proc Natl Acad Sci U S A
; 116(33): 16420-16429, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371506
5.
Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque.
Toxicol Pathol
; 49(3): 602-604, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856568
6.
Tolerability Assessment of Formulation pH in New Zealand White Rabbits Following Intravitreal Administration.
Toxicol Pathol
; 49(3): 605-609, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33252028
7.
Fab-Nanolipoprotein Conjugate Causes Vitreous Opacity and Cataracts Following a Single Intravitreal Administration in New Zealand White Rabbits.
Toxicol Pathol
; 49(3): 647-655, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733956
8.
Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins.
Toxicol Pathol
; 49(3): 634-646, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349160
9.
An anti-CD3/anti-CLL-1 bispecific antibody for the treatment of acute myeloid leukemia.
Blood
; 129(5): 609-618, 2017 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908880
10.
Idiopathic Colitis in Rhesus Macaques Is Associated With Dysbiosis, Abundant Enterochromaffin Cells and Altered T-Cell Cytokine Expression.
Vet Pathol
; 55(5): 741-752, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29929446
11.
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease.
J Med Chem
; 67(5): 3287-3306, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431835
12.
Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys.
AAPS J
; 25(4): 64, 2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353723
13.
Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.
Biochem J
; 432(3): 505-14, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20929438
14.
An integrated approach for characterizing immunogenic responses toward a bispecific antibody.
MAbs
; 13(1): 1944017, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34225571
15.
In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection.
Toxicol Sci
; 169(2): 409-421, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796434
16.
Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia.
MAbs
; 10(8): 1312-1321, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30183491
17.
The cytochrome P450 family in the parasitic nematode Haemonchus contortus.
Int J Parasitol
; 45(4): 243-51, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558056
18.
The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice.
J Gerontol A Biol Sci Med Sci
; 70(10): 1181-8, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313149
19.
The influence of Shc proteins on life span in mice.
J Gerontol A Biol Sci Med Sci
; 69(10): 1177-85, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24336818
20.
Metastatic hepatocellular carcinoma in a juvenile rhesus macaque (Macaca mulatta).
Comp Med
; 63(5): 448-53, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24210023