Detalhe da pesquisa
1.
Copper(I)-Catalyzed Nitrile-Addition/N-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6H-indolo[3,2-c]quinolin-6-ones as Potent Topoisomerase-I Inhibitors.
J Med Chem
; 64(3): 1435-1453, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33492141
2.
Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.
Eur J Med Chem
; 191: 112118, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32113126
3.
Nicotine stimulates expression of the PNMT gene through a novel promoter sequence.
J Mol Neurosci
; 26(1): 39-55, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15968085
4.
Discovery of 4-aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: optimization of in vitro potencies and pharmacokinetic properties.
J Med Chem
; 57(10): 4098-110, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24773549
5.
Synthesis and antiproliferative activities of ottelione a analogues.
ACS Med Chem Lett
; 3(12): 1075-80, 2012 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900431