Detalhe da pesquisa
1.
A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Anti-Mycobacterial Activity.
Antimicrob Agents Chemother
; 95(5)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33558292
2.
Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection.
Antimicrob Agents Chemother
; 67(2): e0145922, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36688684
3.
Assay development and inhibition of the Mt-DprE2 essential reductase from Mycobacterium tuberculosis.
Microbiology (Reading)
; 169(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36748627
4.
GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment.
Antimicrob Agents Chemother
; 66(6): e0013222, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35607978
5.
A Mycobacterium tuberculosis NBTI DNA Gyrase Inhibitor Is Active against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 65(12): e0151421, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606340
6.
Lack of Specificity of Phenotypic Screens for Inhibitors of the Mycobacterium tuberculosis FAS-II System.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139282
7.
The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
J Biol Chem
; 293(22): 8379-8393, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632076
8.
Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis.
Anal Biochem
; 567: 30-37, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30543804
9.
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661879
10.
Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism.
J Antimicrob Chemother
; 73(2): 395-403, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29177421
11.
A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.
Mol Microbiol
; 101(3): 515-29, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27121350
12.
A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents.
Malar J
; 15(1): 385, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27448565
13.
Combinations of ß-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection.
Antimicrob Agents Chemother
; 59(8): 4997-9, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25987618
14.
Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.
Antimicrob Agents Chemother
; 59(6): 3298-305, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801574
15.
Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
Antimicrob Agents Chemother
; 57(7): 3268-74, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629698
16.
Red blood cells derived from peripheral blood and bone marrow CD34⺠human haematopoietic stem cells are permissive to Plasmodium parasites infection.
Mem Inst Oswaldo Cruz
; 108(6): 801-3, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24037205
17.
The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation.
Cell Surf
; 7: 100068, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34888432
18.
Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism.
Antimicrob Agents Chemother
; 54(5): 1872-7, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20160056
19.
Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline.
FASEB Bioadv
; 2(10): 600-612, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33089076
20.
Development of a whole-cell high-throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis.
FASEB Bioadv
; 1(4): 246-254, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32123830