Detalhe da pesquisa
1.
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Nat Chem Biol
; 17(1): 113-121, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33082574
2.
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Proc Natl Acad Sci U S A
; 117(45): 28046-28055, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093202
3.
Exploring the Evolutionary History of Kinetic Stability in the α-Lytic Protease Family.
Biochemistry
; 60(3): 170-181, 2021 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433210
4.
Evolutionary trend toward kinetic stability in the folding trajectory of RNases H.
Proc Natl Acad Sci U S A
; 113(46): 13045-13050, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799545
5.
The burst-phase folding intermediate of ribonuclease H changes conformation over evolutionary history.
Biopolymers
; 109(8): e23086, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29152711
6.
Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5.
Biochemistry
; 54(9): 1767-77, 2015 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25664683
7.
The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins.
Protein Sci
; 33(6): e5011, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747388
8.
The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins.
bioRxiv
; 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37425932
9.
Engineering interferons and interleukins for cancer immunotherapy.
Adv Drug Deliv Rev
; 182: 114112, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35085624
10.
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.
J Clin Invest
; 132(4)2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35166238
11.
CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease.
Clin Cancer Res
; 28(14): 3066-3075, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35604681
12.
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Nat Cell Biol
; 24(1): 24-34, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027731
13.
Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2.
MAbs
; 13(1): 1893426, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33666135
14.
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
Nat Biotechnol
; 39(8): 928-935, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33767397
15.
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
bioRxiv
; 2021 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33501440
16.
Split enzymes: Design principles and strategy.
Methods Enzymol
; 644: 275-296, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32943149
17.
A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding.
medRxiv
; 2020 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511506
18.
Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding.
mSphere
; 5(5)2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938700
19.
Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike.
bioRxiv
; 2020 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817948
20.
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
medRxiv
; 2020 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32839788