Detalhe da pesquisa
1.
A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell
; 185(19): 3533-3550.e27, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36113427
2.
A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding.
J Biol Chem
; 299(7): 104901, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37302550
3.
High integrin αVß6 affinity reached by hybrid domain deletion slows ligand-binding on-rate.
Proc Natl Acad Sci U S A
; 115(7): E1429-E1436, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378937
4.
ß-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbß3 Headpiece.
J Biol Chem
; 291(9): 4537-46, 2016 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631735
5.
E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors.
Proc Natl Acad Sci U S A
; 108(40): 16515-20, 2011 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930946
6.
Mechanism of action and inhibition of dehydrosqualene synthase.
Proc Natl Acad Sci U S A
; 107(50): 21337-42, 2010 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21098670
7.
Terpene biosynthesis: modularity rules.
Angew Chem Int Ed Engl
; 51(5): 1124-37, 2012 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22105807
8.
Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP.
Biochem J
; 429(3): 485-95, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20497125
9.
Diterpene cyclases and the nature of the isoprene fold.
Proteins
; 78(11): 2417-32, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20602361
10.
Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
J Am Chem Soc
; 131(14): 5153-62, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19309137
11.
A putative polyketide-synthesis protein XC5357 from Xanthomonas campestris: heterologous expression, crystallization and preliminary X-ray analysis.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 7): 697-9, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511132
12.
Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators.
Angew Chem Int Ed Engl
; 49(6): 1136-8, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20039246
13.
Head-to-head prenyl tranferases: anti-infective drug targets.
J Med Chem
; 55(9): 4367-72, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22486710
14.
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
J Med Chem
; 52(13): 3869-80, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19456099
15.
Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.
J Med Chem
; 52(4): 976-88, 2009 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19191557
16.
Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
ChemMedChem
; 7(4): 561-4, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22290830
17.
NMR structure note--solution structure of a bacterial BolA-like protein XC975 from a plant pathogen Xanthomonas campestris pv. campestris.
J Biomol NMR
; 31(2): 167-72, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15772757