Detalhe da pesquisa
1.
Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers.
Proc Natl Acad Sci U S A
; 117(37): 23182-23190, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873645
2.
Genome-scale metabolic modeling reveals key features of a minimal gene set.
Mol Syst Biol
; 17(7): e10099, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34288418
3.
Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth.
PLoS Comput Biol
; 17(6): e1007817, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161321
4.
Cellular responses to reactive oxygen species are predicted from molecular mechanisms.
Proc Natl Acad Sci U S A
; 116(28): 14368-14373, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31270234
5.
Genome-scale model of metabolism and gene expression provides a multi-scale description of acid stress responses in Escherichia coli.
PLoS Comput Biol
; 15(12): e1007525, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31809503
6.
BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data.
PLoS Comput Biol
; 15(4): e1006971, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31009451
7.
The genetic basis for adaptation of model-designed syntrophic co-cultures.
PLoS Comput Biol
; 15(3): e1006213, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30822347
8.
Global transcriptional regulatory network for Escherichia coli robustly connects gene expression to transcription factor activities.
Proc Natl Acad Sci U S A
; 114(38): 10286-10291, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874552
9.
COBRAme: A computational framework for genome-scale models of metabolism and gene expression.
PLoS Comput Biol
; 14(7): e1006302, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975681
10.
Systems biology definition of the core proteome of metabolism and expression is consistent with high-throughput data.
Proc Natl Acad Sci U S A
; 112(34): 10810-5, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261351
11.
Laboratory Evolution to Alternating Substrate Environments Yields Distinct Phenotypic and Genetic Adaptive Strategies.
Appl Environ Microbiol
; 83(13)2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28455337
12.
solveME: fast and reliable solution of nonlinear ME models.
BMC Bioinformatics
; 17(1): 391, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27659412
13.
Pangenome analysis of Enterobacteria reveals richness of secondary metabolite gene clusters and their associated gene sets.
Synth Syst Biotechnol
; 7(3): 900-910, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647330
14.
Reconstructing organisms in silico: genome-scale models and their emerging applications.
Nat Rev Microbiol
; 18(12): 731-743, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958892
15.
DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression.
BMC Syst Biol
; 13(1): 2, 2019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626386
16.
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.
Nat Commun
; 9(1): 5252, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30531987
17.
Principles of proteome allocation are revealed using proteomic data and genome-scale models.
Sci Rep
; 6: 36734, 2016 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27857205
18.
Next-generation genome-scale models for metabolic engineering.
Curr Opin Biotechnol
; 35: 23-9, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25575024
19.
iML1515, a knowledgebase that computes Escherichia coli traits.
Nat Biotechnol
; 35(10): 904-908, 2017 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29020004