Detalhe da pesquisa
1.
Interaction of quercetin and its derivatives with Ca2+-ATPase from sarcoplasmic reticulum: Kinetic and molecular modeling studies.
Gen Physiol Biophys
; 42(5): 457-468, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37702450
2.
Synthesis and structure-activity relationship of berkeleylactone A-derived antibiotics.
Org Biomol Chem
; 20(39): 7821-7832, 2022 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36169622
3.
Chemistry towards Biology-Instruct: Snapshot.
Int J Mol Sci
; 23(23)2022 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499140
4.
Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications.
Molecules
; 26(10)2021 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34066081
5.
Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents.
Drug Dev Res
; 81(2): 215-231, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471933
6.
Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors.
Molecules
; 24(23)2019 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757051
7.
Synthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking.
Bioorg Chem
; 78: 280-289, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29621640
8.
Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity.
Bioorg Med Chem
; 25(24): 6353-6360, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074349
9.
Inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA1) by rutin derivatives.
J Muscle Res Cell Motil
; 36(2): 183-94, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467059
10.
Rutin stimulates sarcoplasmic reticulum Ca(2+)-ATPase activity (SERCA1) and protects SERCA1 from peroxynitrite mediated injury.
Mol Cell Biochem
; 402(1-2): 51-62, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25547066
11.
2-Chloro-1,4-naphthoquinone derivative of quercetin as an inhibitor of aldose reductase and anti-inflammatory agent.
J Enzyme Inhib Med Chem
; 30(1): 107-13, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24666303
12.
Protection or cytotoxicity mediated by a novel quinonoid-polyphenol compound?
Gen Physiol Biophys
; 34(1): 51-64, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367759
13.
Novel quercetin derivatives in treatment of peroxynitrite-oxidized SERCA1.
Mol Cell Biochem
; 386(1-2): 1-14, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24141791
14.
Inhibitors of SARS-CoV-2 main protease: Biological efficacy and toxicity aspects.
Toxicol In Vitro
; 92: 105640, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37419426
15.
Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group.
Eur J Med Chem
; 246: 114922, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36455357
16.
Polyphenol fatty acid esters as serine protease inhibitors: a quantum-chemical QSAR analysis.
J Enzyme Inhib Med Chem
; 27(6): 800-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21981000
17.
Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship.
Gen Physiol Biophys
; 30(4): 342-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131315
18.
Structural Changes of Sarco/Endoplasmic Reticulum Ca2+-ATPase Induced by Rutin Arachidonate: A Molecular Dynamics Study.
Biomolecules
; 10(2)2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024167
19.
(4-Oxo-2-thioxothiazolidin-3-yl)acetic acids as potent and selective aldose reductase inhibitors.
Chem Biol Interact
; 332: 109286, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33038328
20.
Phenolic Compounds from Morus nigra Regulate Viability and Apoptosis of Pancreatic ß-Cells Possibly via SERCA Activity.
ACS Med Chem Lett
; 11(5): 1006-1013, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435418