Detalhe da pesquisa
1.
Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of Ace1 point mutations.
PLoS Genet
; 18(2): e1009963, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143477
2.
The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites.
PLoS Biol
; 19(12): e3001483, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34879056
3.
Drug Repurposing in the Chemotherapy of Infectious Diseases.
Molecules
; 29(3)2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338378
4.
Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense.
Molecules
; 29(7)2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611890
5.
Structure-Activity Relationships and Antiplasmodial Potencies of Novel 3,4-Disubstituted 1,2,5-Oxadiazoles.
Int J Mol Sci
; 24(19)2023 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833929
6.
Editorial : Swiss TPH: 30 Years of R&D Towards New Drugs for Tropical Diseases.
Chimia (Aarau)
; 77(9): 570-571, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047831
7.
Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute.
Chimia (Aarau)
; 77(9): 582-592, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047834
8.
Key Contributions by the Swiss Tropical and Public Health Institute Towards New and Better Drugs for Tropical Diseases.
Chimia (Aarau)
; 77(9): 593-602, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047835
9.
2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study.
Molecules
; 27(17)2022 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36080325
10.
Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54.
Molecules
; 27(19)2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235096
11.
Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids.
Molecules
; 28(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615504
12.
Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores.
Molecules
; 27(19)2022 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234752
13.
Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity.
Molecules
; 27(7)2022 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408605
14.
Salvia officinalis L.: Antitrypanosomal Activity and Active Constituents against Trypanosoma brucei rhodesiense.
Molecules
; 26(11)2021 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34072147
15.
Boswellic Acids Show In Vitro Activity against Leishmania donovani.
Molecules
; 26(12)2021 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34203815
16.
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction.
Molecules
; 26(20)2021 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684761
17.
The Alkaloid-Enriched Fraction of Pachysandra terminalis (Buxaceae) Shows Prominent Activity against Trypanosoma brucei rhodesiense.
Molecules
; 26(3)2021 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33498621
18.
Niclosamide Is Active In Vitro against Mycetoma Pathogens.
Molecules
; 26(13)2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209118
19.
8-Amino-6-Methoxyquinoline-Tetrazole Hybrids: Impact of Linkers on Antiplasmodial Activity.
Molecules
; 26(18)2021 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34577001
20.
Antiprotozoal Structure-Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action.
Angew Chem Int Ed Engl
; 60(28): 15613-15621, 2021 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730410