Detalhe da pesquisa
1.
Modular cytosine base editing promotes epigenomic and genomic modifications.
Nucleic Acids Res
; 52(2): e8, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994786
2.
Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice.
Nucleic Acids Res
; 50(14): 8093-8106, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849338
3.
Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes.
Proc Natl Acad Sci U S A
; 118(29)2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253616
4.
The role of HIRA-dependent H3.3 deposition and its modifications in the somatic hypermutation of immunoglobulin variable regions.
Proc Natl Acad Sci U S A
; 118(50)2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873043
5.
Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection.
PLoS Pathog
; 17(4): e1009560, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33930088
6.
STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes.
PLoS Pathog
; 16(10): e1008849, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33002095
7.
A Bayesian model based computational analysis of the relationship between bisulfite accessible single-stranded DNA in chromatin and somatic hypermutation of immunoglobulin genes.
PLoS Comput Biol
; 17(9): e1009323, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34491985
8.
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.
Blood
; 133(22): 2401-2412, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975638
9.
A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks.
BMC Evol Biol
; 19(1): 149, 2019 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31337330
10.
The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure.
BMC Bioinformatics
; 19(1): 163, 2018 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716522
11.
Correction to: The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure.
BMC Bioinformatics
; 19(1): 256, 2018 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29973133
12.
The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes.
PLoS Comput Biol
; 13(3): e1005471, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28362825
13.
Overlapping hotspots in CDRs are critical sites for V region diversification.
Proc Natl Acad Sci U S A
; 112(7): E728-37, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25646473
14.
Potential for evolution of complex defense strategies in a multi-scale model of virus-host coevolution.
BMC Evol Biol
; 16(1): 233, 2016 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27784264
15.
Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks.
PLoS Comput Biol
; 11(10): e1004432, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26451700
16.
Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity?
PLoS Comput Biol
; 10(3): e1003450, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24604070
17.
A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.
Proc Natl Acad Sci U S A
; 109(10): 3832-7, 2012 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22357756
18.
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.
Blood
; 120(24): 4802-11, 2012 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23071276
19.
The underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks.
PLoS Comput Biol
; 9(1): e1002865, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300434
20.
Evolvability of cancer-associated genes under APOBEC3A/B selection.
iScience
; 27(4): 109433, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38550998