Detalhe da pesquisa
1.
Selective killing of human breast cancer cells by the styryl lactone (R)-goniothalamin is mediated by glutathione conjugation, induction of oxidative stress and marked reactivation of the R175H mutant p53 protein.
Carcinogenesis
; 39(11): 1399-1410, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010803
2.
Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid.
Bioorg Med Chem Lett
; 26(12): 2829-2833, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27156773
3.
XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies.
Mol Cancer Ther
; 23(4): 421-435, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030380
4.
An Asp to Strike Out Cancer? Therapeutic Possibilities Arising from Aspartate's Emerging Roles in Cell Proliferation and Survival.
Biomolecules
; 11(11)2021 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34827664
5.
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction.
Cancer Res
; 80(17): 3492-3506, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32651261
6.
Characterization of a highly specific NQO1-activated near-infrared fluorescent probe and its application for in vivo tumor imaging.
Sci Rep
; 9(1): 8577, 2019 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31189950
7.
Cancer-Specific Biomarker hNQO1-Activatable Fluorescent Probe for Imaging Cancer Cells In Vitro and In Vivo.
Cancers (Basel)
; 10(12)2018 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30487423
8.
S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells.
Neoplasia
; 20(4): 305-323, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510343
9.
Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts.
Oncotarget
; 9(3): 3459-3482, 2018 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29423059
10.
Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies.
Cancers (Basel)
; 10(2)2018 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439493
11.
Conception, synthesis, and characterization of a rofecoxib-combretastatin hybrid drug with potent cyclooxygenase-2 (COX-2) inhibiting and microtubule disrupting activities in colon cancer cell culture and xenograft models.
Oncotarget
; 9(40): 26109-26129, 2018 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899846
12.
The Process and Regulatory Components of Inflammation in Brain Oncogenesis.
Biomolecules
; 7(2)2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346397
13.
Design and synthesis of a C7-aryl piperlongumine derivative with potent antimicrotubule and mutant p53-reactivating properties.
Eur J Med Chem
; 107: 233-44, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26599530
14.
Posttranslational Regulation of O(6)-Methylguanine-DNA Methyltransferase (MGMT) and New Opportunities for Treatment of Brain Cancers.
Mini Rev Med Chem
; 16(6): 455-64, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26202203
15.
New insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy.
J Biomed Res
; 30(5): 393-410, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27845303