Detalhe da pesquisa
1.
Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Proc Natl Acad Sci U S A
; 120(32): e2217800120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498871
2.
The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Br J Pharmacol
; 180(9): 1267-1285, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245395
3.
Conditional knockout of CRMP2 in neurons, but not astrocytes, disrupts spinal nociceptive neurotransmission to control the initiation and maintenance of chronic neuropathic pain.
Pain
; 163(2): e368-e381, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35029600
4.
Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15.
Mol Brain
; 14(1): 20, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33478555
5.
Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific Nav1.7 regulation in the pathogenesis of chronic neuropathic pain.
Pain
; 161(11): 2629-2651, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32569093
6.
Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief.
Channels (Austin)
; 13(1): 498-504, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31680630
7.
The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.
ACS Chem Neurosci
; 10(12): 4834-4846, 2019 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697467
8.
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.
Pain
; 160(1): 117-135, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30169422