Detalhe da pesquisa
1.
Discovery of Potent, Reversible, and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach.
J Chem Inf Model
; 60(2): 1028-1041, 2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31765144
2.
Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria.
J Nat Prod
; 81(5): 1203-1208, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29757646
3.
Recent Advances and Perspectives in Cancer Drug Design.
An Acad Bras Cienc
; 90(1 Suppl 2): 1233-1250, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29768576
4.
Semisynthesis of new aphidicolin derivatives with high activity against Trypanosoma cruzi.
Bioorg Med Chem Lett
; 26(4): 1205-8, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26810263
5.
Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics.
Front Pharmacol
; 12: 774069, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35069198
6.
A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity.
Front Oncol
; 10: 1528, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33042796
7.
Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity.
Front Chem
; 7: 798, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31824926
8.
Discovery of a Series of Acridinones as Mechanism-Based Tubulin Assembly Inhibitors with Anticancer Activity.
PLoS One
; 11(8): e0160842, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27508497