Detalhe da pesquisa
1.
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
Am J Hum Genet
; 110(7): 1200-1206, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311464
2.
PU.1 controls fibroblast polarization and tissue fibrosis.
Nature
; 566(7744): 344-349, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700907
3.
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants.
Am J Hum Genet
; 99(4): 877-885, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27666373
4.
AA9int: SNP interaction pattern search using non-hierarchical additive model set.
Bioinformatics
; 34(24): 4141-4150, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29878078
5.
gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels.
Genet Epidemiol
; 41(4): 297-308, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28211093
6.
A low-frequency haplotype spanning SLX4/FANCP constitutes a new risk locus for early-onset breast cancer (<60 years) and is associated with reduced DNA repair capacity.
Int J Cancer
; 142(4): 757-768, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29044504
7.
Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status.
Hum Mol Genet
; 25(24): 5490-5499, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798103
8.
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array.
Br J Cancer
; 118(6): e9, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438362
9.
SNP interaction pattern identifier (SIPI): an intensive search for SNP-SNP interaction patterns.
Bioinformatics
; 33(6): 822-833, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039167
10.
Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies.
Genet Epidemiol
; 40(6): 461-9, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312771
11.
Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study.
Int J Cancer
; 140(1): 75-85, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27643404
12.
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis.
Int J Cancer
; 140(2): 322-328, 2017 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27741566
13.
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Hum Mol Genet
; 24(19): 5589-602, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26025378
14.
Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages.
Ann Rheum Dis
; 76(6): 1133-1141, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28209630
15.
Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis.
Ann Rheum Dis
; 76(11): 1941-1948, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814429
16.
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
Ann Rheum Dis
; 76(4): 773-778, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28153829
17.
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer.
PLoS Genet
; 10(2): e1004129, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550738
18.
Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.
Int J Cancer
; 139(7): 1520-33, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27225428
19.
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array.
Br J Cancer
; 114(8): 945-52, 2016 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26964030
20.
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium.
Br J Cancer
; 115(5): 624-31, 2016 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27490808