Detalhe da pesquisa
1.
2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
Proc Natl Acad Sci U S A
; 118(21)2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972410
2.
A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
J Bacteriol
; 204(5): e0055521, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35435721
3.
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat Chem Biol
; 13(9): 943-950, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671682
4.
Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase.
Chem Res Toxicol
; 32(3): 456-466, 2019 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30746940
5.
A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity.
J Biol Chem
; 290(9): 5893-911, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25572472
6.
Native Mass Spectrometry Dissects the Structural Dynamics of an Allosteric Heterodimer of SARS-CoV-2 Nonstructural Proteins.
J Am Soc Mass Spectrom
; 35(5): 912-921, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38535992
7.
Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
iScience
; 27(2): 108976, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38327783
8.
Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis.
J Biol Chem
; 287(19): 16058-72, 2012 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22408253
9.
A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
Microbiol Resour Announc
; 12(10): e0050723, 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37747257
10.
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Biochemistry
; 51(31): 6148-63, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22788966
11.
High-throughput protein purification and quality assessment for crystallization.
Methods
; 55(1): 12-28, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21907284
12.
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore.
Proc Natl Acad Sci U S A
; 106(51): 21854-9, 2009 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19955416
13.
Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens.
Microbiol Spectr
; 10(2): e0013922, 2022 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35195438
14.
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Proc Natl Acad Sci U S A
; 105(44): 17133-8, 2008 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18955706
15.
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Commun Biol
; 4(1): 193, 2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33564093
16.
Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
Protein Sci
; 30(9): 1904-1918, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34107106
17.
The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Staphylococcus aureus Infections.
ACS Infect Dis
; 7(11): 3062-3076, 2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34590817
18.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Science
; 373(6557): 931-936, 2021 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285133
19.
Cleavable C-terminal His-tag vectors for structure determination.
J Struct Funct Genomics
; 11(1): 31-9, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20213425
20.
Structural and biochemical analysis of the metallo-ß-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity.
Protein Sci
; 29(3): 723-743, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31846104