Detalhe da pesquisa
1.
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
Mol Cell
; 71(4): 629-636.e5, 2018 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118681
2.
E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis.
Mol Cell
; 54(6): 987-998, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882208
3.
Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Proc Natl Acad Sci U S A
; 116(33): 16420-16429, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371506
4.
TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.
Mol Cell
; 48(6): 888-99, 2012 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142077
5.
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.
Proc Natl Acad Sci U S A
; 112(18): 5679-84, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902490
6.
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
J Immunol
; 192(7): 3259-68, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24610009
7.
Activation of the PERK branch of the unfolded protein response during production reduces specific productivity in CHO cells via downregulation of PDGFRa and IRE1a signaling.
Biotechnol Prog
; 39(5): e3354, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37161726
8.
Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET.
J Biol Chem
; 286(37): 32762-74, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21784853
9.
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay.
Nat Commun
; 13(1): 1587, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332141
10.
Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation.
J Cell Biol
; 221(6)2022 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446348
11.
Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Sci Transl Med
; 14(641): eabl8146, 2022 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35442706
12.
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.
Cell Metab
; 34(9): 1377-1393.e8, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987202
13.
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Nat Commun
; 12(1): 7310, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911951
14.
Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.
Elife
; 92020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31904339
15.
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Cancer Res
; 80(11): 2368-2379, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32265225
16.
Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress.
Elife
; 82019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31453810
17.
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
MAbs
; 11(6): 996-1011, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31156033
18.
Activation of the proapoptotic death receptor DR5 by oligomeric peptide and antibody agonists.
J Mol Biol
; 361(3): 522-36, 2006 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16859704
19.
Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey.
Cell Death Dis
; 7(8): e2338, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27512959
20.
Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity.
Mol Cancer Ther
; 14(10): 2270-8, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269606