Detalhe da pesquisa
1.
Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability.
Circ Res
; 122(11): 1501-1516, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29514831
2.
Tbx20 controls the expression of the KCNH2 gene and of hERG channels.
Proc Natl Acad Sci U S A
; 114(3): E416-E425, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049825
3.
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters.
Nat Commun
; 14(1): 89, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609575
4.
Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel.
J Gen Physiol
; 153(5)2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33779689
5.
The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval.
Sci Rep
; 10(1): 10707, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612162
6.
Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels.
JCI Insight
; 3(18)2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232268
7.
Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone.
Front Physiol
; 8: 903, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29184507
8.
Pitx2c increases in atrial myocytes from chronic atrial fibrillation patients enhancing IKs and decreasing ICa,L.
Cardiovasc Res
; 109(3): 431-41, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26714926
9.
Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels.
Cardiovasc Res
; 110(2): 279-90, 2016 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26786162
10.
Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.
Cardiovasc Res
; 104(2): 337-46, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25205296
11.
Chronic atrial fibrillation increases microRNA-21 in human atrial myocytes decreasing L-type calcium current.
Circ Arrhythm Electrophysiol
; 7(5): 861-8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25107449
12.
Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore.
Biochem Pharmacol
; 86(2): 267-78, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23648307
13.
Functional characterization of a novel frameshift mutation in the C-terminus of the Nav1.5 channel underlying a Brugada syndrome with variable expression in a Spanish family.
PLoS One
; 8(11): e81493, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24363796