Implant Strength Contributes to the Osseointegration Strength of Porous Metallic Materials.

Creating the optimal environment for effective and long term osseointegration is a heavily researched and sought-after design criteria for orthopedic implants. A validated multimaterial finite element (FE) model was developed to replicate and understand the results of an experimental in vivo push-out osseointegration model. The FE model results closely predicted global force (at 0.5 mm) and stiffness for the 50-90% porous implants with an r2 of 0.97 and 0.98, respectively. In addition, the FE global force at 0.5 mm showed a correlation to the maximum experimental forces with an r2 of 0.90. The highest porosity implants (80-90%) showed lower stiffnesses and more equitable load sharing but also failed at lower a global force level than the low porosity implants (50-70%). The lower strength of the high porosity implants caused premature plastic deformation of the implant itself during loading as well as significant deformations in the ingrown and surrounding bone, resulting in lower overall osseointegration strength, consistent with experimental measurements. The lower porosity implants showed a balance of sufficient bony ingrowth to support osseointegration strength coupled with implant mechanical properties to circumvent significant implant plasticity and collapse under the loading conditions. Together, the experimental and finite element modeling results support an optimal porosity in the range of 60-70% for maximizing osseointegration with current structure and loading.

Finite element modeling of the free boundary effect on gyroid additively manufactured samples.

There is a significant need for models that can capture the mechanical behavior of complex porous lattice architectures produced by 3D printing. The free boundary effect is an experimentally observed behavior of lattice architectures including the gyroid triply periodic minimal surface where the number of unit cell repeats has been shown to influence the mechanical performance of the lattice. The purpose of this study is to use finite element modeling to investigate how architecture porosity, unit cell size, and sample size dictate mechanical behavior. Samples with varying porosity and increasing number of unit cells (relative to sample size) were modeled under an axial compressive load to determine the effective modulus. The finite element model captured the free boundary effect and captured experimental trends in the structure's modulus. The findings of this study show that samples with higher porosity are more susceptible to the impact of the free boundary effect and in some samples, the modulus can be 20% smaller in samples with smaller numbers of unit cell repeats within a given sample boundary. The outcomes from this study provide a deeper understanding of the gyroid structure and the implications of design choices including porosity, unit cell size, and overall sample size.

A bending model for assessing relative stiffness and strength of orthopaedic fixation constructs.

BACKGROUND: The purpose of this study is to develop a simple and reproducible bending model that is compatible with a wide range of orthopaedic fixation devices and 3D printed spacers. METHODS: A robust 4-point bending model was constructed by securing sawbones blocks with different orthopaedic fixation device constructs. Stress strain curves derived from a fundamental mechanics model were used to assess the effect of bone density, type of hardware (staple vs intramedullary beam), the use of dynamic compression, orientation of staples (dorsal vs plantar), and the use of 3D printed titanium spacers. FINDINGS: The high throughput 4-point bending model is simple enough that the methods can be easily repeated to assess a wide range of fixation methods, while complex enough to provide clinically relevant information. INTERPRETATIONS: It is recommended that this model is used to assess a large initial set of fixation methods in direct and straightforward comparisons.

Tensile performance data of 3D printed photopolymer gyroid lattices.

Additive manufacturing has provided the ability to manufacture complex structures using a wide variety of materials and geometries. Structures such as triply periodic minimal surface (TPMS) lattices have been incorporated into products across many fields due to their unique combinations of mechanical, geometric, and physical properties. Yet, the near limitless possibility of combining geometry and material into these lattices leaves much to be discovered. This article provides a dataset of experimentally gathered tensile stress-strain curves and measured porosity values for 389 unique gyroid lattice structures manufactured using vat photopolymerization 3D printing. The lattice samples were printed from one of twenty different photopolymer materials available from either Formlabs, LOCTITE AM, or ETEC that range from strong and brittle to elastic and ductile and were printed on commercially available 3D printers, specifically the Formlabs Form2, Prusa SL1, and ETEC Envision One cDLM Mechanical. The stress-strain curves were recorded with an MTS Criterion C43.504 mechanical testing apparatus and following ASTM standards, and the void fraction or "porosity" of each lattice was measured using a calibrated scale. This data serves as a valuable resource for use in the development of novel printing materials and lattice geometries and provides insight into the influence of photopolymer material properties on the printability, geometric accuracy, and mechanical performance of 3D printed lattice structures. The data described in this article was used to train a machine learning model capable of predicting mechanical properties of 3D printed gyroid lattices based on the base mechanical properties of the printing material and porosity of the lattice in the research article [1].