Detalhe da pesquisa
1.
Discovery and structure-activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors.
Bioorg Med Chem Lett
; 26(17): 4179-83, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499455
2.
Quinol derivatives as potential trypanocidal agents.
Bioorg Med Chem
; 20(4): 1607-15, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22264753
3.
Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions.
Org Biomol Chem
; 8(9): 2078-84, 2010 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20401384
4.
Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.
J Med Chem
; 51(4): 963-75, 2008 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18247546
5.
Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions.
J Med Chem
; 50(7): 1707-10, 2007 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17343370
6.
Programming Organic Molecules: Design and Management of Organic Syntheses through Free-Radical Cascade Processes.
Angew Chem Int Ed Engl
; 40(12): 2224-2248, 2001 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-11433483
7.
Antitumor quinols: role of glutathione in modulating quinol-induced apoptosis and identification of putative cellular protein targets.
Biochem Biophys Res Commun
; 346(1): 242-51, 2006 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16756956
8.
Synthesis and properties of bioactive 2- and 3-amino-8-methyl-8H-quino[4,3,2-kl]acridine and 8,13-dimethyl-8H-quino[4,3,2-kl]acridinium salts.
Org Biomol Chem
; 2(2): 220-8, 2004 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-14737646
9.
Studies on high-temperature amination reactions of aromatic chlorides using discrete palladium-N-heterocyclic carbene (NHC) complexes and in situ palladium/imidazolium salt protocols.
Mol Divers
; 7(2-4): 115-23, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14870840