Detalhe da pesquisa
1.
A systematic review and meta-analysis of tau phosphorylation in mouse models of familial Alzheimer's disease.
Neurobiol Dis
; 192: 106427, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38307366
2.
Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy.
Exp Brain Res
; 237(10): 2645-2651, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31388734
3.
Bis-pyridylethenyl benzene as novel backbone for amyloid-ß binding compounds.
Bioorg Med Chem
; 24(23): 6139-6148, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27838168
4.
Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-d-aspartate receptor as potential imaging probes for positron emission tomography.
Bioorg Med Chem
; 23(5): 1189-206, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25648682
5.
Structure-activity relationships of N-substituted 4-(trifluoromethoxy)benzamidines with affinity for GluN2B-containing NMDA receptors.
Bioorg Med Chem Lett
; 24(3): 828-30, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412068
6.
Polyfluorinated bis-styrylbenzenes as amyloid-ß plaque binding ligands.
Bioorg Med Chem
; 22(8): 2469-81, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24657049
7.
Natural antioxidants that act against Alzheimer's disease through modulation of the NRF2 pathway: a focus on their molecular mechanisms of action.
Front Endocrinol (Lausanne)
; 14: 1217730, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37465125
8.
Efficacy of Chronic Paroxetine Treatment in Mitigating Amyloid Pathology and Microgliosis in APPSWE/PS1ΔE9 Transgenic Mice.
J Alzheimers Dis
; 87(2): 685-699, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35342093
9.
Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions.
Cells
; 10(3)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803476
10.
Mild Microglial Responses in the Cortex and Perivascular Macrophage Infiltration in Subcortical White Matter in Dogs with Age-Related Dementia Modelling Prodromal Alzheimer's Disease.
J Alzheimers Dis
; 82(2): 575-592, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34057083
11.
Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding.
Eur J Neurosci
; 31(4): 742-53, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20384817
12.
Differential region-specific regulation of α4ß2* nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice.
Addict Biol
; 15(4): 464-79, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20731631
13.
Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease.
Alzheimers Res Ther
; 11(1): 38, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31043179
14.
Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer's Disease Patients.
Front Cell Neurosci
; 13: 538, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31866830
15.
Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
Sci Rep
; 9(1): 15758, 2019 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31673052
16.
Binding characterization of N-(2-chloro-5-thiomethylphenyl)-N'-(3-[3 H]3 methoxy phenyl)-N'-methylguanidine ([3 H]GMOM), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist.
Pharmacol Res Perspect
; 7(1): e00458, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784206
17.
Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer's Disease.
J Alzheimers Dis
; 64(4): 1247-1259, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29991132
18.
Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 Month Old APPswe/PSEN1dE9 Mice.
Curr Alzheimer Res
; 15(5): 420-428, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28982335
19.
Established amyloid-ß pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.
Alzheimers Dement (N Y)
; 4: 215-223, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29955664
20.
First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors.
EJNMMI Res
; 8(1): 69, 2018 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054846