Detalhe da pesquisa
1.
In vitro and In Vivo Immunomodulatory Activity of Physalis angulata Concentrated Ethanolic Extract.
Planta Med
; 87(1-02): 160-168, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32937664
2.
Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Bioorg Med Chem
; 26(20): 5388-5396, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293795
3.
Aryl thiosemicarbazones: In vitro and immunomodulatory activities against L. amazonensis.
Exp Parasitol
; 177: 57-65, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28433563
4.
Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents.
Bioorg Med Chem
; 24(22): 5693-5701, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27667552
5.
Antiparasitic evaluation of betulinic acid derivatives reveals effective and selective anti-Trypanosoma cruzi inhibitors.
Exp Parasitol
; 166: 108-15, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27080160
6.
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles.
Antimicrob Agents Chemother
; 58(1): 352-63, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24165185
7.
Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity.
J Nat Prod
; 77(6): 1345-50, 2014 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24871307
8.
Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity.
J Enzyme Inhib Med Chem
; 29(2): 230-6, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23432595
9.
hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
ACS Med Chem Lett
; 15(4): 463-469, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628794
10.
Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions.
Retrovirology
; 10: 153, 2013 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24330857
11.
Chemical and Pharmacological Properties of Decoquinate: A Review of Its Pharmaceutical Potential and Future Perspectives.
Pharmaceutics
; 14(7)2022 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890280
12.
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp.
Front Pharmacol
; 13: 846123, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35392556
13.
A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Stem Cells Int
; 2021: 2642807, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34434238
14.
Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities.
Bioorg Med Chem
; 18(18): 6857-64, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20719524
15.
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.
Bioorg Med Chem
; 18(22): 7826-35, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20961766
16.
In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.
Front Pharmacol
; 11: 590544, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33390966
17.
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents.
Bioorg Med Chem
; 17(18): 6682-91, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19683450
18.
Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.
Bioorg Med Chem
; 17(14): 5038-43, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19539479
19.
Anti-inflammatory activity of SintMed65, an N-acylhydrazone derivative, in a mouse model of allergic airway inflammation.
Int Immunopharmacol
; 75: 105735, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31306982
20.
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization.
Front Immunol
; 10: 1257, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31244833