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Infection ; 43(3): 267-76, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25701221

RESUMO

Sporotrichosis is a fungal infection of man and animals caused by Sporothrix complex. It usually presents as a lymphocutaneous form, but disseminated disease may occur. Given the paucity of data about HIV/AIDS and sporotrichosis co-infection, a systematic review of reported cases of HIV-associated sporotrichosis found via Pubmed (1984-2013) was done. A total of 39 papers were included, and 58 patients' data analyzed. Thirty-three (56.9 %) cases were from Brazil and 18 (31 %) from the USA. Patients' mean age was 37.8 ± 10.4 years; males predominated (84.5 %). The median CD4(+) cell count was 97 cells/mm(3). The most common clinical forms were disseminated and disseminated cutaneous with 33 (56.9 %) and 10 (17.5 %) patients, respectively. There was a correlation between CD4(+) count and clinical categories (p = 0.002). Mortality was 30 % and there was a correlation between central nervous system involvement and death (p < 0.001).


Assuntos
Infecções por HIV/complicações , Sporothrix/isolamento & purificação , Esporotricose/epidemiologia , Distribuição por Idade , Animais , Brasil/epidemiologia , Contagem de Linfócito CD4 , Infecções por HIV/imunologia , Humanos , Distribuição por Sexo , Estados Unidos/epidemiologia
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