How to Boost the Impact of Scientific Conferences.

We can maximize the impact of scientific conferences by uploading all conference presentations, posters, and abstracts to highly trafficked public repositories for each content type. Talks can be hosted on sites like YouTube and Youku, posters can be published on Figshare, and papers and abstracts can become open access preprints.

Teaching poster design to enhance research presentation quality at academic conferences: a guide for educators.

Poster sessions are one of the most common platforms for presenting research at academic conferences, yet posters are often inefficient at transferring knowledge to their readers due to suboptimal design and content selection. Physician trainees may not receive education on constructing posters as a traditional part of their residency curriculum. The purpose of this work is to propose a curriculum that will provide residents foundational knowledge and skills needed for designing high-quality research posters. The curriculum uses the flipped classroom model, a pedagogical approach that reverses the traditional learning environment by delivering instructional content outside of the classroom and moves activities into the classroom. Preparatory work includes watching an educational video on 'how to create a better research poster in less time' and preparing a poster to be presented at an upcoming conference. An 1-hour workshop is conducted during protected resident didactic time. It incorporates a 10-min slide show presentation on poster design and 50 min of active learning. During the active learning component, learners are asked to 'think-pair-share' to construct a research poster rubric using the information they just learnt. The learners work as a group to evaluate sample research posters. The class is then broken down into small groups of 2-3 learners to spend time working on their own posters and provide peer feedback. Following the workshop, residents continue to develop their research posters for conference presentation. This curriculum has the potential to enhance the quality of resident research posters presented at academic conferences, advance research education and ultimately improve dissemination of research within academic communities. The lesson plan outlined in this work can be used as a guide for teaching poster design to physician trainees in a number of specialties and may encourage programmes to consider integrating poster design as a formal part of the residency curriculum.

Subjective Well-Being Around the World: Trends and Predictors Across the Life Span.

Using representative cross-sections from 166 nations (more than 1.7 million respondents), we examined differences in three measures of subjective well-being over the life span. Globally, and in the individual regions of the world, we found only very small differences in life satisfaction and negative affect. By contrast, decreases in positive affect were larger. We then examined four important predictors of subjective well-being and how their associations changed: marriage, employment, prosociality, and life meaning. These predictors were typically associated with higher subjective well-being over the life span in every world region. Marriage showed only very small associations for the three outcomes, whereas employment had larger effects that peaked around age 50 years. Prosociality had practically significant associations only with positive affect, and life meaning had strong, consistent associations with all subjective-well-being measures across regions and ages. These findings enhance our understanding of subjective-well-being patterns and what matters for subjective well-being across the life span.

Living among the affluent: boon or bane?

This study examined whether national income can have effects on happiness, or subjective well-being (SWB), over and above those of personal income. To assess the incremental effects of national income on SWB, we conducted cross-sectional multilevel analysis on data from 838,151 individuals in 158 nations. Although greater personal income was consistently related to higher SWB, we found that national income was a boon to life satisfaction but a bane to daily feelings of well-being; individuals in richer nations experienced more worry and anger on average. We also found moderating effects: The income-SWB relationship was stronger at higher levels of national income. This result might be explained by cultural norms, as money is valued more in richer nations. The SWB of more residentially mobile individuals was less affected by national income. Overall, our results suggest that the wealth of the nation one resides in has consequences for one's happiness.

Twitter: More than Tweets for Undergraduate Student Researchers.

During the COVID-19 pandemic, biology educators were forced to think of ways to communicate with their students, engaging them in science and with the scientific community. For educators using course-based undergraduate research experiences (CUREs), the challenge to have students perform real science, analyze their work, and present their results to a larger scientific audience was difficult as the world moved online. Many instructors were able to adapt CUREs utilizing online data analysis and virtual meeting software for class discussions and synchronous learning. However, interaction with the larger scientific community, an integral component of making science relevant for students and allowing them to network with other young scientists and experts in their fields, was still missing. Even before COVID-19, a subset of students would travel to regional or national meetings to present their work, but most did not have these opportunities. With over 300 million active users, Twitter provided a unique platform for students to present their work to a large and varied audience. The Cell Biology Education Consortium hosted an innovative scientific poster session entirely on Twitter to engage undergraduate researchers with one another and with the much broader community. The format for posting on this popular social media platform challenged students to simplify their science and make their points using only a few words and slides. Nineteen institutions and over one hundred students participated in this event. Even though these practices emerged as a necessity during the COVID-19 pandemic, the Twitter presentation strategy shared in this paper can be used widely.

Subjective well-being and national satisfaction: findings from a worldwide survey.

We examined the relationship between satisfaction with one's country (national satisfaction) and subjective well-being utilizing data from a representative worldwide poll. National satisfaction was a strong positive predictor of individual-level life satisfaction, and this relationship was moderated by household income, household conveniences, residential mobility, country gross domestic product per capita, and region (Western vs. non-Western country). When individuals are impoverished or more bound to their culture and surroundings, national satisfaction more strongly predicts life satisfaction. In contrast, reverse trends were found in analyses predicting life satisfaction from satisfaction in other domains (health, standard of living, and job). These patterns suggest that people are more likely to use proximate factors to judge life satisfaction where conditions are salutary, or individualism is salient, but are more likely to use perceived societal success to judge life satisfaction where life conditions are difficult, or collectivism predominates. Our findings invite new research directions and can inform quality-of-life therapies.

Temporal Stability of Implicit and Explicit Measures: A Longitudinal Analysis.

A common assumption about implicit measures is that they reflect early experiences, whereas explicit measures are assumed to reflect recent experiences. This assumption subsumes two distinct hypotheses: (a) Implicit measures are more resistant to situationally induced changes than explicit measures; (b) individual differences on implicit measures are more stable over time than individual differences on explicit measures. Although the first hypothesis has been the subject of numerous studies, the second hypothesis has received relatively little attention. The current research addressed the second hypothesis in two longitudinal studies that compared the temporal stability of individual differences on implicit and explicit measures in three content domains (self-concept, racial attitudes, political attitudes). In both studies, implicit measures showed significantly lower stability over time (weighted average r = .54) than conceptually corresponding explicit measures (weighted average r = .75), despite comparable estimates of internal consistency. Implications for theories of implicit social cognition and interpretations of implicit and explicit measures are discussed.

Analytical and Clinical Validation of Two Commercially Available Immunoassays Used in the Detection of TSHR Antibodies.

BACKGROUND: Graves disease is caused by autoantibodies that target the thyroid-stimulating hormone receptor (TSHR). Anti-TSHR autoantibody measurement is routinely performed to differentiate between Graves disease and other causes of hyperthyroidism. We evaluated the clinical performance of a reference laboratory bioassay [the Thyretain thyroid-stimulating immunoglobulin (TSI) Bioassay by Diagnostic Hybrids] and 2 commercially available immunoassays: the TSI Bridge immunoassay by Siemens and the thyroid-stimulating hormone receptor antibody (TRAb) immunoassay by Roche. We further evaluated the analytical performance of the Siemens TSI and Roche TRAb assays. METHODS: We performed method comparisons using 125 patient specimens submitted for TSI testing for clinical purposes. Concordance of patient results was assessed between the 3 methods, and chart review was performed to further evaluate samples that generated discordant results. All 3 methods were also evaluated for potential interference caused by human chorionic gonadotropin (hCG). RESULTS: The Roche and Siemens assays demonstrated acceptable day-to-day precision, within-run precision, and precision at the clinical decision cutoffs. Despite manufacturer-defined analytical measuring ranges up to 40 IU/L, the Roche and Siemens assays were linear to 20 IU/L and 15 IU/L, respectively. hCG concentrations up to 150000 IU/L did not interfere with any of the methods evaluated. Moderate agreement between methods was observed when testing patient specimens that generated negative (≤1.3) or weakly positive (1.4-3.8) results by the Thyretain assay. One hundred percent agreement was observed when the Thyretain assay was strongly positive (≥3.9). CONCLUSIONS: The 3 commercially available anti-TSHR autoantibody measurement methods demonstrated equivalent performance in patients with untreated Graves disease. Discordant results were observed when testing specimens collected from patients undergoing treatment for Graves disease. In these patients, the Siemens TSI assay more frequently generated results consistent with clinical history, results of other laboratory tests, and imaging studies than the Thyretain Bioassay and Roche TRAb assay.

Stacking the Jury: Legal Professionals' Peremptory Challenges Reflect Jurors' Levels of Implicit Race Bias.

Most legal systems are based on the premise that defendants are treated as innocent until proven guilty and that decisions will be unbiased and solely based on the facts of the case. The validity of this assumption has been questioned for cases involving racial minority members, in that racial bias among jury members may influence jury decisions. The current research shows that legal professionals are adept at identifying jurors with levels of implicit race bias that are consistent with their legal interests. Using a simulated voir dire, professionals assigned to the role of defense lawyer for a Black defendant were more likely to exclude jurors with high levels of implicit race bias, whereas prosecutors of a Black defendant did the opposite. There was no relation between professionals' peremptory challenges and jurors' levels of explicit race bias. Implications for the role of racial bias in legal decision making are discussed.

H2S induces a suspended animation-like state in mice.

Mammals normally maintain their core body temperature (CBT) despite changes in environmental temperature. Exceptions to this norm include suspended animation-like states such as hibernation, torpor, and estivation. These states are all characterized by marked decreases in metabolic rate, followed by a loss of homeothermic control in which the animal's CBT approaches that of the environment. We report that hydrogen sulfide can induce a suspended animation-like state in a nonhibernating species, the house mouse (Mus musculus). This state is readily reversible and does not appear to harm the animal. This suggests the possibility of inducing suspended animation-like states for medical applications.