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Med Mycol ; 52(3): 276-84, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24625676

RESUMO

Favus is a distinctive form of infection that is caused by exclusively dermatophytes. Its clinical presentation is characterized by scutula, which are concave, thick fungal crusts. The best-known examples of human scalp favus are caused by Trichophyton schoenleinii and those of mouse favus are caused by T. quinckeanum. However, other dermatophytes, such as T. violaceum, T. verrucosum, Microsporum audouinii, M. gallinae, M. gypseum, and M. canis, have been reported sporadically to cause favic lesions. Favus on cats has rarely been mentioned in the literature, and the pathogens with which it has been associated are, for the most part, unknown. Here, we examine four cat favus cases, focusing on clinical presentations and histopathological features. In all cases the etiologic agent was identified as M. incurvatum based on its morphological characteristics and sequences of internal transcribed spacers (ITS) of nuclear ribosomal DNA. Phylogenetic analysis using the neighbor-joining method, which is based on ITS, showed that these four isolates belonged to two strains of M. incurvatum; one strain was a new combination from the basionym Nannizzia incurvata.


Assuntos
Doenças do Gato/diagnóstico , Doenças do Gato/patologia , Microsporum/classificação , Microsporum/isolamento & purificação , Tinha Favosa/veterinária , Animais , Doenças do Gato/microbiologia , Gatos , Análise por Conglomerados , DNA Fúngico/química , DNA Fúngico/genética , DNA Espaçador Ribossômico/química , DNA Espaçador Ribossômico/genética , Feminino , Histocitoquímica , Masculino , Camundongos , Microscopia , Microsporum/citologia , Microsporum/genética , Dados de Sequência Molecular , Filogenia , Análise de Sequência de DNA , Tinha Favosa/diagnóstico , Tinha Favosa/microbiologia , Tinha Favosa/patologia
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