Detalhe da pesquisa
1.
Probing the Protein-Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry and Molecular Dynamics.
Anal Chem
; 96(2): 802-809, 2024 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38155586
2.
Drug-Polymer Nanodroplet Formation and Morphology Drive Solubility Enhancement of GDC-0810.
Bioconjug Chem
; 35(4): 499-516, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38546823
3.
Predicting Long-Term Stability of an Oral Delivered Antibody Drug Product with Accelerated Stability Assessment Program Modeling.
Mol Pharm
; 21(1): 325-332, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38060811
4.
Generality of Enhancing the Dissolution Rates of Free Acid Amorphous Solid Dispersions by the Incorporation of Sodium Hydroxide.
Mol Pharm
; 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38836777
5.
Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing.
Mol Pharm
; 21(2): 564-580, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215042
6.
Comparison of mechanochemical methods in the synthesis of binaphthol-benzoquinone based cocrystals.
Phys Chem Chem Phys
; 26(16): 12545-12551, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619480
7.
Development of an Amorphous Solid Dispersion Formulation for Mitigating Mechanical Instability of Crystalline Form and Improving Bioavailability for Early Phase Clinical Studies.
Mol Pharm
; 20(5): 2452-2464, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37010134
8.
Comparative Evaluation of Particle Size Reduction, Salt Formation, and Amorphous Formulation on the Biopharmaceutical Performance of a Weak Base Drug Candidate.
Mol Pharm
; 20(11): 5888-5900, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37792707
9.
Application of resonant acoustic mixing in the synthesis of vitamin C-nicotinamide variable stoichiometry cocrystals.
Faraday Discuss
; 241(0): 357-366, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36196794
10.
The "η-sweet-spot" (ηmax) in liquid-assisted mechanochemistry: polymorph control and the role of a liquid additive as either a catalyst or an inhibitor in resonant acoustic mixing (RAM).
Faraday Discuss
; 241(0): 128-149, 2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239309
11.
Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characterization.
Pharm Res
; 39(12): 3137-3154, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35661085
12.
Determination of BET Specific Surface Area of Hydrate-Anhydrate Systems Susceptible to Phase Transformation Using Inverse Gas Chromatography.
AAPS PharmSciTech
; 23(7): 237, 2022 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002661
13.
Metal-Catalyzed Organic Reactions by Resonant Acoustic Mixing.
Angew Chem Int Ed Engl
; 61(13): e202115030, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35138018
14.
Isothermal Crystallization Monitoring and Time-Temperature-Transformation of Amorphous GDC-0276: Differential Scanning Calorimetric and Rheological Measurements.
Mol Pharm
; 18(1): 158-173, 2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259220
15.
Fast Acquisition of Proton-Detected HETCOR Solid-State NMR Spectra of Quadrupolar Nuclei and Rapid Measurement of NH Bond Lengths by Frequency Selective HMQC and RESPDOR Pulse Sequences.
Chemistry
; 26(35): 7881-7888, 2020 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315472
16.
Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities.
Drug Metab Dispos
; 47(10): 1122-1135, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31266753
17.
Industrial Horizons in Pharmaceutical Science.
Mol Pharm
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38807456
18.
Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS 1H Solid-State NMR Spectroscopy.
Mol Pharm
; 16(7): 3121-3132, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31095913
19.
Correction to "Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing".
Mol Pharm
; 21(6): 3077, 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38663036
20.
Determination of Fragility in Organic Small Molecular Glass Forming Liquids: Comparison of Calorimetric and Spectroscopic Data and Commentary on Pharmaceutical Importance.
Mol Pharm
; 15(3): 1248-1257, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29384682