Detalhe da pesquisa
1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612233
2.
Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes.
Antimicrob Agents Chemother
; 65(5)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33649107
3.
Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection.
Antimicrob Agents Chemother
; 67(1): e0134822, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36519892
4.
Pathological Correlates of Cognitive Decline in Parkinson's Disease: From Molecules to Neural Networks.
Biochemistry (Mosc)
; 88(11): 1890-1904, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105206
5.
Hepatitis B core-specific memory B cell responses associate with clinical parameters in patients with chronic HBV.
J Hepatol
; 73(1): 52-61, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32061650
6.
Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B.
J Hepatol
; 72(1): 34-44, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31348999
7.
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δ.
J Biol Chem
; 290(13): 8439-46, 2015 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631052
8.
New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.
J Biol Chem
; 287(25): 21189-203, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22535962
9.
Impact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitness.
Antimicrob Agents Chemother
; 57(6): 2654-63, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23529738
10.
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.
Biochemistry
; 50(10): 1567-81, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21222490
11.
The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.
J Mol Biol
; 431(7): 1440-1459, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753871
12.
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.
Nat Med
; 25(9): 1377-1384, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501601
13.
Intracardiac lipid accumulation, lipoatrophy of muscle cells and expansion of myocardial infarction in type 2 diabetic patients.
Micron
; 39(7): 944-51, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18093836
14.
PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection.
J Clin Invest
; 128(10): 4573-4587, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30084841
15.
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors.
J Med Chem
; 59(7): 3532-48, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980109
16.
Joint Intratracheal Surfactant-Antibacterial Therapy in Experimental Pseudomonas-Induced Pneumonia.
J Aerosol Med Pulm Drug Deliv
; 28(4): 299-307, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517041