RESUMO
AIM: To report on our routine use of TachoSil® for dural repair in neurosurgical practice. METHOD: TachoSil® has been applied in different fields of surgery thus far. When using TachoSil®, fibrinogen and thrombin is provided locally at the site of the dural defects. Upon contact with fluid, the clotting factors of TachoSil® dissolve and form a fibrin network, which glues the collagen sponge to the wound surface. RESULTS: In our experience, TachoSil® was found to be effective as support for the suture of the dura in patients undergoing spinal and cranial neurosurgical operations. Two illustrative examples are shown. CONCLUSIONS: Our procedure showed that closing the dural defect with TachoSil® is a technically simple, reliable and safe method for patients. Indeed, no post-operative cerebrospinal fluid leakage was observed. Nonetheless, further studies with larger sample size are warranted to confirm the efficacy of TachoSil® patches for dural repair.
Assuntos
Isquemia Encefálica/cirurgia , Dura-Máter/cirurgia , Fibrinogênio , Neoplasias Meníngeas/cirurgia , Meningioma/cirurgia , Procedimentos Neurocirúrgicos , Trombina , Idoso , Combinação de Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , CicatrizaçãoRESUMO
Within the range of validity of the Rytov approximation (RA), an innovative Bayesian compressive sensing (BCS) inverse scattering technique is developed. Potentialities and limitations of the BCS-RA method are validated through numerical experiments and representative results are discussed.
RESUMO
Starting from January 2008, we systematically irrigated the surgical wounds of patients undergoing spine surgery with a solution of povidone-iodine and hydrogen peroxide. We prospectively recorded the clinical data of patients who underwent spine surgery during 2008 and we compared the results with retrospectively reviewed clinical records of patients operated during 2007. Patients were analyzed for preoperative risk factors, type of surgical procedure, onset of infection, presentation, treatment and outcome. We performed 490 spine surgeries during 2008 and 460 during 2007. We recorded four postoperative infections in 2007 compared to none in 2008. We consider this solution of povidone-iodine plus hydrogen peroxide effective to further reduce the rate of post-operative infection in spine surgery.
Assuntos
Anti-Infecciosos Locais/administração & dosagem , Peróxido de Hidrogênio/administração & dosagem , Povidona-Iodo/administração & dosagem , Doenças da Coluna Vertebral/cirurgia , Infecção da Ferida Cirúrgica/prevenção & controle , Anti-Infecciosos Locais/efeitos adversos , Humanos , Peróxido de Hidrogênio/efeitos adversos , Povidona-Iodo/efeitos adversos , Estudos Retrospectivos , Soluções/administração & dosagem , Irrigação Terapêutica/métodosRESUMO
Spheno-orbital meningioma have traditionally been defined as secondary tumors of the orbit originating from the dura of the sphenoid wing bone. Nevertheless, pathologic findings reveal a distinct periorbital component as a defining feature of these lesions. These tumors are characterized by an intraosseous mass growth leading to a significant hyperostosis involving the sphenoid wing, the orbital roof, the lateral orbital wall and the middle fossa cranial base and to a thin, usually soft-tissue growth at the dura. We report here on the extension of the primary tumor into the orbital cavity and present the surgical approach performed.
Assuntos
Meningioma/cirurgia , Neoplasias Orbitárias/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Osteotomia/métodosRESUMO
Rosette-forming glioneuronal tumour (RGNT) of the fourth ventricle is a relatively new entity recently described. Neuronal and mixed neuronal-glial tumours have been incorporated in the same category in the WHO Classification of Nervous System Tumours. This category comprises heterogeneous neoplasms composed of neuronal and glial cells with various grades of differentiation. We present a case of papillary glioneuronal tumor occurring in a 44-year-old man with an unusual hemorrhagic onset. The clinical, morphological and immunohistochemical features are discussed and the published literature is reviewed.
Assuntos
Neoplasias do Ventrículo Cerebral/diagnóstico , Ganglioglioma/diagnóstico , Neoplasias Complexas Mistas/diagnóstico , Adulto , Neoplasias do Ventrículo Cerebral/cirurgia , Craniotomia , Diagnóstico Diferencial , Ganglioglioma/cirurgia , Humanos , Masculino , Neoplasias Complexas Mistas/cirurgia , Prognóstico , Resultado do TratamentoRESUMO
The authors report their surgical experience on 50 patients affected by single or two level segmental lumbar canal stenosis who underwent implantation of one or two X-Stop interspinous devices between October 2007 and February 2008 at the Department of Neurosurgery, "Santa Maria alle Scotte" Hospital, Siena, Italy. In the present study there will be analyzed clinical long-term results and reviewed the relevant literature.
Assuntos
Claudicação Intermitente/cirurgia , Fixadores Internos , Vértebras Lombares/cirurgia , Fusão Vertebral/instrumentação , Estenose Espinal/cirurgia , Adulto , Idoso , Descompressão Cirúrgica/métodos , Feminino , Seguimentos , Humanos , Claudicação Intermitente/diagnóstico , Claudicação Intermitente/etiologia , Tempo de Internação , Vértebras Lombares/patologia , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Seleção de Pacientes , Próteses e Implantes , Estudos Retrospectivos , Fusão Vertebral/métodos , Estenose Espinal/complicações , Estenose Espinal/diagnóstico , Inquéritos e Questionários , Resultado do TratamentoRESUMO
The authors report their surgical experience with 10 cases of anterior subcutaneous ulnar nerve transposition and coverage of the nerve with substitutive dural flap, performed between January and November 2008 at the Department of Neurosurgery ("Santa Maria alle Scotte" Hospital, Siena, Italy) in the treatment of severe cubital tunnel syndrome. Clinical long-term results are analyzed and the relevant literature is reviewed.
Assuntos
Síndrome do Túnel Ulnar/cirurgia , Nervo Ulnar , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos/métodos , Próteses e Implantes , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do TratamentoRESUMO
CASE REPORT: A 70-years-old woman presented with a one week history of progressive loss of vision in the right eye (RE) diagnosed as retinal detachment from 7 to 1 o' clock with retinal break at the 10.30 o' clock associated. Gadolinium enhanced magnetic resonance imaging (MRI) scan of the brain and orbits with fat suppression showed a convexity meningioma. Scleral buckling with a segmental sponge, subretinal fluid drainage and cryopexy were performed with detachment repair. CONCLUSION: In our patient with retinal detachment and convexity meningioma without significant neurological symptoms, performing ocular surgery and close follow up care seemed to be the optimal treatment option.
Assuntos
Neoplasias Meníngeas/complicações , Meningioma/complicações , Descolamento Retiniano/complicações , Idoso , Feminino , HumanosRESUMO
Idiopatic pseudotumor (IP) is a non-specific, non-neoplastic, inflammatory process without identifiable local or systemic causes. IP most commonly affects the orbit, comprising 5% to 8% of all orbital masses with occasional extension to other areas of the skull base. The ophthalmology literature has detailed reviews of IP as a space-occupying intraorbital lesion, but lesion involving only the skull base and sparing the orbit is exceptional. Understanding the presentation, work-up, and characteristics of the lesion is important for proper diagnosis and treatment. We report a rare case of orbital IP with extension into infratemporal fossa. Clinical and radiological findings and surgical approach are discussed.
Assuntos
Doenças Maxilares/etiologia , Pseudotumor Orbitário/complicações , Idoso , Feminino , HumanosRESUMO
AIM: The aim of the study was to assess the efficacy of lumboperitoneal flow-regulated shunt for the treatment of idiopathic intracranial hypertension (IIH). METHODS: This was a retrospective study carried out on four patients with IIH, treated from January to December 2007 with lumboperitoneal flow-regulated shunt (OSV II Smart Valve Systems; Integra NeuroSciences). The mean follow-up period was 13 months. RESULTS: The treatment was successful in alleviating symptoms in all cases and no patient required revisions. CONCLUSIONS: In conclusion the placement of flow-regulated valves is a satisfactory treatment for those IIH patients who require surgical therapy.
Assuntos
Procedimentos Neurocirúrgicos/métodos , Pseudotumor Cerebral/cirurgia , Punção Espinal/métodos , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
Epidural anesthesia is one of the preferred modes of analgesia intra- and postoperative in limb surgery. Although considered very safe, serious complications can occur with 0.1-1 per 10,000 epidural injections. We present a case of a patient who experienced an acute lumbar epidural hematoma after epidural anesthesia.
Assuntos
Analgesia Epidural , Anticoagulantes/efeitos adversos , Enoxaparina/efeitos adversos , Hematoma Epidural Espinal/etiologia , Complicações Pós-Operatórias/etiologia , Punções/efeitos adversos , Idoso de 80 Anos ou mais , Anticoagulantes/uso terapêutico , Artroplastia do Joelho , Enoxaparina/uso terapêutico , Feminino , Hematoma Epidural Espinal/induzido quimicamente , Hematoma Epidural Espinal/cirurgia , Humanos , Laminectomia , Imageamento por Ressonância Magnética , Complicações Pós-Operatórias/induzido quimicamente , Compressão da Medula Espinal/etiologia , Compressão da Medula Espinal/cirurgiaRESUMO
Several complications are known to occur with spinal anaesthesia and all of them are easily recognizable. We report the case of a 25 year old woman presenting with intracerebral hemorrhage secondary to spinal anaesthesia for caesarean section. She underwent surgical evacuation of the haematoma with complete recovery. The relevant literature is also reviewed.
Assuntos
Raquianestesia/efeitos adversos , Cesárea , Hematoma Subdural Intracraniano/etiologia , Hematoma Subdural Intracraniano/cirurgia , Adulto , Feminino , Cefaleia/etiologia , Hematoma Subdural Intracraniano/diagnóstico , Hemiplegia/etiologia , Humanos , Gravidez , Resultado do TratamentoRESUMO
Malignant brain neoplasms have a poor prognosis despite aggressive treatments. Animal models and evidence from human bodily tumors reveal that sustained reduction in tumor perfusion via electrical stimulation promotes tumor necrosis, therefore possibly representing a therapeutic option for patients with brain tumors. Here, we demonstrate that transcranial electrical stimulation (tES) allows to safely and noninvasively reduce intratumoral perfusion in humans. Selected patients with glioblastoma or metastasis underwent tES, while perfusion was assessed using magnetic resonance imaging. Multichannel tES was applied according to personalized biophysical modeling, to maximize the induced electrical field over the solid tumor mass. All patients completed the study and tolerated the procedure without adverse effects, with tES selectively reducing the perfusion of the solid tumor. Results potentially open the door to noninvasive therapeutic interventions in brain tumors based on stand-alone tES or its combination with other available therapies.
Assuntos
Neoplasias Encefálicas/terapia , Glioblastoma/terapia , Estimulação Transcraniana por Corrente Contínua/métodos , Idoso , Antineoplásicos/uso terapêutico , Circulação Cerebrovascular/fisiologia , Terapia Combinada , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-IdadeRESUMO
Herniated thoracic disks are rare entities and their surgical treatment comprises 0.15% to 4% of all disk operations. Surgical approaches have included pediculectomy, costotransversectomy, lateral extracavitary, transthoracic thoracotomy, and thoracoscopy. The authors present a transmanubrial osteomuscular sparing approach for the treatment of T1-T2 thoracic disc herniation that is likely to be the only one described in the literature for this disease so far.
Assuntos
Deslocamento do Disco Intervertebral/cirurgia , Manúbrio/cirurgia , Procedimentos Neurocirúrgicos , Vértebras Torácicas , Idoso , Humanos , Deslocamento do Disco Intervertebral/diagnóstico , Imageamento por Ressonância Magnética , Masculino , Próteses e Implantes , Implantação de Prótese , Titânio , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
Solitary eosinophilic granuloma is a rather benign and localized form of Langerhans's cell histiocytosis. Definitive diagnosis is made by histopathology including immunohistochemical detection of S-100, HLA-DR and CD1a antigens. We report the case of a twenty-five year old boy presented with headache and orbit's pain. A CT scan showed a left supero-lateral orbital mass with evidence of bone erosion. The different options of treatment are discussed and the literature is reviewed.
Assuntos
Histiocitose de Células de Langerhans , Neoplasias Orbitárias , Adulto , Biomarcadores/metabolismo , Histiocitose de Células de Langerhans/diagnóstico , Histiocitose de Células de Langerhans/patologia , Humanos , Masculino , Neoplasias Orbitárias/diagnóstico , Neoplasias Orbitárias/patologiaRESUMO
Intracerebral haemorrhages occurring after removal of chronic subdural haematoma have been reported as a rare but nearly uniformly devastating postoperative occurrence with incidence ranges between 0,7 and 5%. The absence of a particular attention paid to such complication in literature prompted us to present this report adding our personal experience to the cases already described in the literature.
Assuntos
Hemorragia Cerebral/etiologia , Hemorragia Cerebral/cirurgia , Hematoma Subdural Crônico/complicações , Hematoma Subdural Crônico/cirurgia , Procedimentos Neurocirúrgicos/efeitos adversos , Idoso de 80 Anos ou mais , Hemorragia Cerebral/diagnóstico por imagem , Evolução Fatal , Hematoma Subdural Crônico/diagnóstico por imagem , Humanos , Masculino , Período Pós-Operatório , Tomografia Computadorizada por Raios XRESUMO
Capnocytophaga canimorsus has been recognized as an opportunistic pathogen causing systemic infections in immunocompromised individuals. It is part of the normal oral flora of the dog, and can be responsible for localized wound infections in humans in consequence of bites. This microorganism causes also septicemia, meningitis, endocarditis, ocular infections and rarely brain abscess. We describe the case of an immunocompetent 28-year-old male with temporal brain abscess from Capnocytophaga canimorsus secondary to dog's bite.
Assuntos
Mordeduras e Picadas/complicações , Abscesso Encefálico/etiologia , Capnocytophaga , Cães , Infecções por Bactérias Gram-Negativas , Adulto , Animais , Antibacterianos/uso terapêutico , Abscesso Encefálico/diagnóstico , Abscesso Encefálico/microbiologia , Abscesso Encefálico/cirurgia , Capnocytophaga/isolamento & purificação , Seguimentos , Infecções por Bactérias Gram-Negativas/cirurgia , Humanos , Imageamento por Ressonância Magnética , Masculino , Cuidados Pós-Operatórios , Fatores de Tempo , Resultado do TratamentoRESUMO
The case of a 51-year-old man presented with intermittent diplopia, headache and family history of Rendu-Olser-Weber disease , also defined heredirary hemorrhagic telangiectasia (HHT), is described. Magnetic resonance imaging of the brain revealed an enhancing right occipital mass with surrounding edema. Computerized tomography of the chest identified pulmonary arteriovenous fistlae. The physiopathology of HHT and the treatment of the cerebral lesions are discussed.
Assuntos
Fístula Artério-Arterial/complicações , Fístula Artério-Arterial/patologia , Abscesso Encefálico/complicações , Artéria Pulmonar/anormalidades , Artéria Pulmonar/patologia , Telangiectasia Hemorrágica Hereditária/complicações , Antibacterianos/uso terapêutico , Fístula Artério-Arterial/diagnóstico por imagem , Abscesso Encefálico/tratamento farmacológico , Abscesso Encefálico/patologia , Infarto Encefálico/complicações , Craniotomia , Diplopia/etiologia , Cefaleia/etiologia , Humanos , Embolia Intracraniana/complicações , Embolia Intracraniana/patologia , Embolia Intracraniana/fisiopatologia , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Lobo Occipital/microbiologia , Lobo Occipital/patologia , Lobo Occipital/fisiopatologia , Artéria Pulmonar/diagnóstico por imagem , Telangiectasia Hemorrágica Hereditária/patologia , Telangiectasia Hemorrágica Hereditária/fisiopatologia , Tomografia Computadorizada por Raios X , Vancomicina/uso terapêuticoRESUMO
A case of acute subdural haematoma of the posterior fossa in an alive adult secondary to anticoagulant therapy is described. The clinical presentation and the final decision of conservative management are discussed and the literature is reviewed.
Assuntos
Anticoagulantes/efeitos adversos , Fossa Craniana Posterior/patologia , Hematoma Subdural Agudo/induzido quimicamente , Hematoma Subdural Agudo/patologia , Fatores Etários , Idoso de 80 Anos ou mais , Doença de Alzheimer/complicações , Encéfalo/diagnóstico por imagem , Encéfalo/patologia , Fossa Craniana Posterior/diagnóstico por imagem , Cefaleia/etiologia , Hematoma Subdural Agudo/diagnóstico por imagem , Humanos , Masculino , Procedimentos Neurocirúrgicos/normas , Pancreatite Crônica/complicações , Medição de Risco , Tomografia Computadorizada por Raios X , Trombose Venosa/tratamento farmacológico , Vertigem/etiologiaRESUMO
The case of an 18-year-old primipara in the second trimester of pregnancy affected by a primitive supratentorial mass is described. Main symptoms of increased intracranial pressure were severe headache, diplopia, and left hemiparesis. In the 20(th) week of pregnancy a fronto-temporal craniotomy was performed with complete excision of the tumor. Immunohistochemical analysis showed a primitive neuroectodermal tumor (PNET). Three months after being discharged, the patient still presented headache and apathy, and a magnetic resonance imaging scan again showed the presence of a temporal lesion; therefore, after caesarean delivery the second surgical resection of the tumor was performed. Combined chemotherapy and radiotherapy was required.