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1.
Pediatr Diabetes ; 18(4): 315-319, 2017 06.
Artigo em Inglês | MEDLINE | ID: mdl-27161659

RESUMO

BACKGROUND/OBJECTIVE: The impact of family composition on glycemic control in children with type 1 diabetes remains unclear. We sought to evaluate the relationship between health insurance coverage, family composition, and insulin management, and assess their impact on glycemic control in a pediatric type 1 diabetes population. METHODS: A retrospective chart review was completed for patients seen in the Pediatric Endocrinology Clinic at the University of Louisville in 2012. RESULTS: The analysis included 729 patients with type 1 diabetes; 268 (37%) had public insurance while 461(63%) had private insurance. Compared with publicly insured patients, privately insured patients had higher rates of intensive insulin management with multiple daily injections (MDI) plans or pump devices (88 vs. 83.2%, p = 0.066) and lower HbA1c levels [8.57 vs. 9.39% (70 vs. 79 mmol/mol), p < 0.001]. Of the 729 patients, 243 were in single-adult homes (33%). Single-adult homes had higher HbA1c levels than two-adult homes, [9.3 vs. 8.6% (78 vs. 70 mmol/mol), p < 0.001]. Among publicly insured, there was no difference in HbA1c levels for single-adult vs. two-adult homes [9.4 (79 mmol/mol), p = 0.868]. For privately insured, patients in single-adult homes had higher HbA1c levels than peers in two-adult homes [9.2 vs. 8.4% (77 vs. 68), p < 0.001]. CONCLUSION: Insurance type and family composition have significant associative effects on glycemic control and insulin management that may be mitigated by insulin pump therapy. Identifying and addressing factors such as availability of resources, family education, and adult support and supervision, may help improve glycemic control in high-risk pediatric diabetes patients.


Assuntos
Diabetes Mellitus Tipo 1/tratamento farmacológico , Família , Hiperglicemia/prevenção & controle , Hipoglicemiantes/administração & dosagem , Insulina/administração & dosagem , Seguro Saúde , Autogestão , Biomarcadores/sangue , Estudos de Coortes , Terapia Combinada/economia , Diabetes Mellitus Tipo 1/sangue , Diabetes Mellitus Tipo 1/economia , Diabetes Mellitus Tipo 1/terapia , Esquema de Medicação , Feminino , Hemoglobinas Glicadas/análise , Gastos em Saúde , Hospitais Universitários , Humanos , Hiperglicemia/economia , Hipoglicemiantes/economia , Hipoglicemiantes/uso terapêutico , Insulina/economia , Insulina/uso terapêutico , Sistemas de Infusão de Insulina/economia , Kentucky , Masculino , Ambulatório Hospitalar , Estudos Retrospectivos , Autogestão/economia , Pais Solteiros
2.
J Pediatr Endocrinol Metab ; 28(5-6): 721-4, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25581742

RESUMO

We report a 9-year-old female who presented with new onset intractable seizure activity followed by a prolonged encephalopathic state. After ruling out common etiologies, Hashimoto's encephalopathy (HE) was considered, and antibody levels to thyroid peroxidase and thyroglobulin were both markedly elevated in her serum. She was euthyroid at the time of presentation. Upon treatment with high dose methylprednisolone, the patient demonstrated a significant improvement in her encephalopathy. The diagnosis of HE requires strong clinical suspicion with evidence of antithyroid antibodies, as well as an encephalopathy not explained by another etiology. While well documented in the adult literature, only a handful of pediatric cases have been described to date. Patients with HE have a nearly universal response to high dose glucocorticoids. HE should be considered in the differential diagnosis of any patient, adult or pediatric, who displays prolonged, unexplainable encephalopathy.


Assuntos
Encefalite/diagnóstico , Doença de Hashimoto/diagnóstico , Criança , Encefalite/complicações , Encefalite/tratamento farmacológico , Feminino , Doença de Hashimoto/complicações , Doença de Hashimoto/tratamento farmacológico , Humanos , Imageamento por Ressonância Magnética , Metilprednisolona/uso terapêutico , Convulsões/complicações
3.
Diabetes Res Clin Pract ; 90(1): 40-4, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20630611

RESUMO

AIMS: To examine the association between health insurance coverage, insulin management plans, and their impact on diabetes control in a pediatric type 1 diabetes mellitus clinic population. METHODS: Retrospective cohort design drawn from the medical records of the Pediatric Endocrinology Clinic at the University of Louisville, Kentucky. RESULTS: Out of 701 patients, 223 had public insurance, and 478 had private insurance. 77% of publically insured used two or three injections per day vs. 40% private. Conversely, 58% of privately insured used a multiple daily injection (MDI) plan or insulin pump (vs. 21%). 84% of MDI patients had private insurance with 93% using insulin pens compared with 38% of publically insured. Mean HbA1c was 8.6% for privately insured vs. 9.8% public, p<0.0001. Privately insured MDI and pump patients had the lowest HbA1cs. CONCLUSIONS: Insurance type had a significant effect on the insulin management plan used and was the most significant factor in overall diabetes control. Limitations on insulin pen use and number of glucose test strips may play a role in the decreased use of MDI/insulin pumps by publicly insured patients. Addressing factors related to insurance type, including availability of resources, could substantially improve diabetes control in those with public insurance.


Assuntos
Diabetes Mellitus Tipo 1/tratamento farmacológico , Diabetes Mellitus Tipo 1/economia , Hipoglicemiantes/uso terapêutico , Insulina/uso terapêutico , Cobertura do Seguro/estatística & dados numéricos , Seguro Saúde , Adolescente , Automonitorização da Glicemia/economia , Criança , Pré-Escolar , Estudos de Coortes , Diabetes Mellitus Tipo 1/sangue , Feminino , Hemoglobinas Glicadas/análise , Hospitais Universitários , Humanos , Hipoglicemiantes/administração & dosagem , Hipoglicemiantes/economia , Insulina/administração & dosagem , Insulina/economia , Sistemas de Infusão de Insulina/estatística & dados numéricos , Masculino , Prontuários Médicos , National Health Insurance, United States , Ambulatório Hospitalar/estatística & dados numéricos , Estudos Retrospectivos , Estados Unidos , Adulto Jovem
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