Detalhe da pesquisa
1.
Focus on senescence: Clinical significance and practical applications.
J Intern Med
; 295(5): 599-619, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446642
2.
Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy.
Alzheimers Dement
; 20(2): 783-797, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777848
3.
Effect of ethanol and cocaine on [11C]MPC-6827 uptake in SH-SY5Y cells.
Mol Biol Rep
; 48(4): 3871-3876, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33880672
4.
Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).
Am J Primatol
; 83(11): e23260, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33818801
5.
Can oral health and oral-derived biospecimens predict progression of dementia?
Oral Dis
; 26(2): 249-258, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31541581
6.
Mammalian Target of Rapamycin at the Crossroad Between Alzheimer's Disease and Diabetes.
Adv Exp Med Biol
; 1128: 185-225, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31062331
7.
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.
Biochim Biophys Acta
; 1852(10 Pt A): 2213-24, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248058
8.
Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.
Neurochem Res
; 41(7): 1625-34, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26935741
9.
Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.
Proc Natl Acad Sci U S A
; 110(46): 18698-703, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24173031
10.
Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.
J Neurochem
; 134(3): 538-50, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940666
11.
Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.
Arch Biochem Biophys
; 576: 8-16, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25841340
12.
A Need for Refined Senescence Biomarkers and Measures of Senolytics in the Brain.
J Alzheimers Dis
; 98(2): 411-415, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38461508
13.
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment.
Geroscience
; 46(1): 665-682, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994989
14.
Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer's Disease.
Res Sq
; 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496619
15.
Senolytic therapy to modulate the progression of Alzheimer's Disease (SToMP-AD) - Outcomes from the first clinical trial of senolytic therapy for Alzheimer's disease.
Res Sq
; 2023 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162971
16.
Preliminary PET Imaging of Microtubule-Based PET Radioligand [11C]MPC-6827 in a Nonhuman Primate Model of Alzheimer's Disease.
ACS Chem Neurosci
; 14(20): 3745-3751, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37724996
17.
Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial.
Nat Med
; 29(10): 2481-2488, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679434
18.
Biological aging processes underlying cognitive decline and neurodegenerative disease.
J Clin Invest
; 132(10)2022 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35575089
19.
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system.
Prog Neurobiol
; 208: 102181, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34670118
20.
Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling.
Acta Neuropathol Commun
; 10(1): 23, 2022 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164877