Detalhe da pesquisa
1.
Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.
Cell
; 175(5): 1244-1258.e26, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30454645
2.
Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.
J Biol Chem
; 292(34): 14108-14121, 2017 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28684421
3.
Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.
Bioorg Med Chem Lett
; 27(14): 3117-3122, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28571824
4.
Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.
Amino Acids
; 46(3): 701-15, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23881108
5.
Histone 3.3 participates in a self-sustaining cascade of apoptosis that contributes to the progression of chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
; 188(6): 673-83, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23924319
6.
Translational control of Nrf2 within the open reading frame.
Biochem Biophys Res Commun
; 437(1): 134-9, 2013 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23806685
7.
Identification of Inhibitors of Tubulin Polymerization Using a CRISPR-Edited Cell Line with Endogenous Fluorescent Tagging of ß-Tubulin and Histone H1.
Biomolecules
; 13(2)2023 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36830618
8.
CRISPR/Cas9-Based Screening of FDA-Approved Drugs for NRF2 Activation: A Novel Approach to Discover Therapeutics for Non-Alcoholic Fatty Liver Disease.
Antioxidants (Basel)
; 12(7)2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507903
9.
Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction-associated steatohepatitis by amplifying TGFß signaling in hepatic stellate cells.
Sci Transl Med
; 15(715): eade2966, 2023 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37756380
10.
Dosing strategies for de novo once-daily extended release tacrolimus in kidney transplant recipients based on CYP3A5 genotype.
World J Transplant
; 13(6): 368-378, 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38174147
11.
Extracellular Acetylated Histone 3.3 Induces Inflammation and Lung Tissue Damage.
Biomolecules
; 13(9)2023 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759735
12.
Regulation of polyamine metabolism by translational control.
Amino Acids
; 42(2-3): 611-7, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21811825
13.
Pneumocystis S-adenosylmethionine transport: a potential drug target.
Am J Respir Cell Mol Biol
; 45(6): 1142-6, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21642588
14.
Multiplex Gene Tagging with CRISPR-Cas9 for Live-Cell Microscopy and Application to Study the Role of SARS-CoV-2 Proteins in Autophagy, Mitochondrial Dynamics, and Cell Growth.
CRISPR J
; 4(6): 854-871, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34847745
15.
Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer.
ACS Med Chem Lett
; 11(11): 2156-2164, 2020 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214824
16.
Passive transfer of Plasmodium falciparum MSP-2 pseudopeptide-induced antibodies efficiently controlled parasitemia in Plasmodium berghei-infected mice.
Peptides
; 30(2): 330-42, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19071172
17.
A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase.
Curr Pharm Des
; 20(2): 245-52, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23701549
18.
Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase.
Mol Cell Biol
; 32(8): 1453-67, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22354986
19.
Mechanism and tissue specificity of nicotine-mediated lung S-adenosylmethionine reduction.
J Biol Chem
; 283(12): 7690-6, 2008 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-18180293
20.
Identifying and characterising the Plasmodium falciparum RhopH3 Plasmodium vivax homologue.
Biochem Biophys Res Commun
; 358(3): 861-6, 2007 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17511961