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1.
Prev Sci ; 24(2): 204-213, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-33880691

RESUMO

Family-based preventive interventions have been found to prevent youth internalizing symptoms, yet they operate through diverse mechanisms with heterogeneous effects for different youth. To better target preventive interventions, this study examines the effects of the Familias Unidas preventive intervention on reducing internalizing symptoms with a universal sample of Hispanic youth in a real-world school setting (i.e., effectiveness trial). The study utilizes emerging methods in baseline target moderated mediation (BTMM) to determine whether the intervention reduces internalizing symptoms through its impact on three distinct mechanisms: family functioning, parent stress, and social support for parents. Data are from a randomized controlled effectiveness trial of 746 Hispanic eighth graders and their parents assessed at baseline, 6-, 18-, and 30-month post-baseline. BTMM models examined three moderated mechanisms through which the intervention might influence 30-month adolescent internalizing symptoms. The intervention decreased youth internalizing symptoms through improvements in family functioning in some models, but there was no evidence of moderation by baseline level of family functioning. There was some evidence of mediation through increasing social support for parents for those intervention parents presenting with lower baseline support. However, there was no evidence of mediation through parent stress. Post hoc analyses suggest a possible cascading of effects where improvements in support for parents strengthened parental monitoring of youth and ultimately reduced youth internalizing symptoms. Findings support the intervention's effects on internalizing symptoms in a universal, real-world setting, and the value of BTMM methods to improve the targeting of preventive interventions. ClinicalTrials.gov Identifier: NCTO1038206, First Posted: December 23, 2009.


Assuntos
Hispânico ou Latino , Pais , Humanos , Adolescente , Apoio Social
2.
Br J Psychiatry ; 215(2): 476-480, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31190652

RESUMO

BACKGROUND: Neighbourhood greenness or vegetative presence has been associated with indicators of health and well-being, but its relationship to depression in older adults has been less studied. Understanding the role of environmental factors in depression may inform and complement traditional depression interventions, including both prevention and treatment.AimsThis study examines the relationship between neighbourhood greenness and depression diagnoses among older adults in Miami-Dade County, Florida, USA. METHOD: Analyses examined 249 405 beneficiaries enrolled in Medicare, a USA federal health insurance programme for older adults. Participants were 65 years and older, living in the same Miami location across 2 years (2010-2011). Multilevel analyses assessed the relationship between neighbourhood greenness, assessed by average block-level normalised difference vegetative index via satellite imagery, and depression diagnosis using USA Medicare claims data. Covariates were individual age, gender, race/ethnicity, number of comorbid health conditions and neighbourhood median household income. RESULTS: Over 9% of beneficiaries had a depression diagnosis. Higher levels of greenness were associated with lower odds of depression, even after adjusting for demographics and health comorbidities. When compared with individuals residing in the lowest tertile of greenness, individuals from the middle tertile (medium greenness) had 8% lower odds of depression (odds ratio 0.92; 95% CI 0.88, 0.96; P = 0.0004) and those from the high tertile (high greenness) had 16% lower odds of depression (odds ratio 0.84; 95% CI 0.79, 0.88; P < 0.0001). CONCLUSIONS: Higher levels of greenness may reduce depression odds among older adults. Increasing greenery - even to moderate levels - may enhance individual-level approaches to promoting wellness.Declaration of interestNone.


Assuntos
Depressão/epidemiologia , Meio Ambiente , Características de Residência , Idoso , Idoso de 80 Anos ou mais , Feminino , Florida/epidemiologia , Humanos , Renda , Modelos Logísticos , Masculino , Medicare , Plantas , Estudos Retrospectivos , Imagens de Satélites , Estados Unidos
3.
Prev Med ; 120: 85-99, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30610888

RESUMO

The objectives of this systematic review were to: 1) identify evidence-based youth (i.e., infancy, pre-school age, school age, and adolescence) mental and behavioral health disorder preventive interventions conducted in or offered by primary care settings, and 2) describe these interventions' characteristics, efficacy, and clinical involvement. Randomized controlled trials that targeted the prevention of mental or behavioral health outcomes for youth and had a connection to primary care were included. The PRISMA guidelines were utilized for two phases: 1) searching PubMed, EMBASE, PsycInfo, CINAHL, and Cochrane databases in January 2017; and 2) searching United States Preventive Services Task Force (USPSTF) Systematic Reviews in November 2017. The two phases revealed 504 and 58 potential articles, respectively. After removal of duplicates, screening of abstracts, and full-text reviews, 19 interventions (infancy: n = 2, pre-school age: n = 3, school age: n = 6, adolescence: n = 8) were included: 1) 10 interventions described in 17 articles from the databases, and 2) 9 interventions described in 11 articles from the USPSTF reviews. The included interventions capitalized on primary care settings as a natural entry point to engage youth and families into interventions without requiring a large amount of clinic involvement. Commonalities of efficacious interventions and recommendations for future research are discussed. The authors encourage primary care providers, mental and behavioral health providers, and/or public health researchers to continue developing and testing preventive interventions, or adapting existing interventions, to be implemented in primary care.


Assuntos
Transtornos Mentais/prevenção & controle , Saúde Mental , Serviços Preventivos de Saúde/organização & administração , Prevenção Primária/organização & administração , Adolescente , Criança , Pré-Escolar , Medicina Baseada em Evidências , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Masculino , Transtornos Mentais/epidemiologia , Avaliação de Programas e Projetos de Saúde , Ensaios Clínicos Controlados Aleatórios como Assunto , Medição de Risco , Estados Unidos , Adulto Jovem
4.
J Adolesc ; 72: 91-100, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30877842

RESUMO

INTRODUCTION: The pervasive use of technology has raised concerns about its association with adolescent mental health, including internalizing symptoms. Existing studies have not always had consistent findings. Longitudinal research with diverse subgroups is needed. METHODS: This study examines the relationship between screen-based sedentary (SBS) behaviors and internalizing symptoms among 370 Hispanic adolescents living in Miami, Florida- United States, who were followed for 2 ½ years and assessed at baseline, 6, 18 and 30 months post-baseline between the years 2010 and 2014. Approximately 48% were girls, and 44% were foreign-born, most of these youth being from Cuba. Mean age at baseline was 13.4 years, while at the last time-point it was 15.9 years. RESULTS: Findings show that girls had higher internalizing symptoms and different patterns of screen use compared to boys, including higher phone, email, and text use. SBS behaviors and internalizing symptoms cooccurred at each time-point, and their trajectories were significantly related (r = 0.45, p < .001). Cross-lagged panel analyses found that SBS behaviors were not associated with subsequent internalizing symptoms. Among girls, however, internalizing symptoms were associated with subsequent SBS behaviors during later adolescence, with internalizing symptoms at the 18-month assessment (almost 15 years old) associated with subsequent SBS behaviors at the 30-month assessment (almost 16 years old; ß = 0.20, p < .01). CONCLUSIONS: Continued research and monitoring of internalizing symptoms and screen use among adolescents is important, especially among girls. This includes assessments that capture quantity, context, and content of screen time.


Assuntos
Mecanismos de Defesa , Tempo de Tela , Comportamento Sedentário , Adolescente , Comportamento do Adolescente , Feminino , Florida , Hispânico ou Latino/psicologia , Humanos , Estudos Longitudinais , Masculino , Estados Unidos
5.
Prev Sci ; 19(Suppl 1): 1-5, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29368296

RESUMO

We introduce this supplemental issue of Prevention Science, which brings together a set of papers from leading investigators who have conducted trials testing whether intervention programs prevent adolescent depression. Using data from these trials, these papers explore a series of factors that might account for variation in intervention benefit, employing several novel methods for assessing effect heterogeneity. These studies follow two general paradigms: three papers report findings from single randomized preventive intervention trials, while the remaining papers develop and apply new methods for combining data from multiple studies to evaluate effect heterogeneity more broadly. Colleagues from NIMH and SAMHSA also provide commentaries on these studies. They conclude that synthesis of findings from multiple trials holds great promise for advancing the field, and progress will be accelerated if collaborative data sharing becomes the norm rather than the exception.


Assuntos
Depressão/prevenção & controle , Promoção da Saúde , Adolescente , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto
6.
Prev Sci ; 19(Suppl 1): 49-59, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-27318951

RESUMO

Prevention programs that strengthen parenting and family functioning have been found to reduce poor behavioral outcomes in adolescents, including substance use, HIV risk, externalizing and internalizing problems. However, there is evidence that not all youth benefit similarly from these programs. Familias Unidas is a family-focused intervention designed to prevent substance use and sexual risk among Hispanic youth and has recently demonstrated unanticipated reductions in internalizing symptoms for some youth. This paper examines variation in intervention response for internalizing symptoms using individual-level data pooled across four distinct Familias Unidas trials: (1) 266 eighth grade students recruited from the general school population; (2) 160 ninth grade students from the general school population; (3) 213 adolescents with conduct, aggression, and/or attention problems; and (4) 242 adolescents with a delinquency history. Causal inference growth mixture modeling suggests a three-class model. The two largest classes represent youth with low (60 %) and medium (27 %) internalizing symptoms at baseline, and both intervention and control participants show reductions in internalizing symptoms. The third class (13 %) represents youth with high levels of baseline internalizing symptoms who remain at steady levels of internalizing symptoms when exposed to the intervention, but who experience an increase in symptoms under the control condition. Female gender, low baseline levels of parent-adolescent communication, and older age were associated with membership in the high-risk class. These synthesis analyses involving a large sample of youth with varying initial risk levels represent a further step toward strengthening our knowledge of preventive intervention response and improving preventive interventions.


Assuntos
Ansiedade/prevenção & controle , Depressão/prevenção & controle , Promoção da Saúde , Hispânico ou Latino/psicologia , Poder Familiar , Avaliação de Programas e Projetos de Saúde , Adolescente , Transtorno da Conduta/prevenção & controle , Feminino , Humanos , Delinquência Juvenil/prevenção & controle , Masculino , Serviços Preventivos de Saúde
7.
Prev Sci ; 19(5): 630-641, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-27704326

RESUMO

The Familias Unidas intervention is an efficacious family-based preventive intervention for reducing substance use and other health risks among Hispanic youth. A current randomized controlled trial (RCT) is examining this intervention's efficacy when delivered via the Internet (eHealth). eHealth interventions can overcome logistical barriers to participation, yet there is limited information about the feasibility of these interventions, especially among ethnic minorities. This paper examines participation and predictors of participation in the eHealth Familias Unidas intervention in a sample of 113 Hispanic families whose adolescent had behavioral problems. Analyses examined multidimensional ways of characterizing participation, including the following: (1) total intervention participation, (2) initial engagement (participating in at least one of the first three intervention sessions), (3) completing the pre-recorded, eHealth parent group sessions, and (4) participating in the live, facilitator-led, eHealth family sessions. Participation in this eHealth intervention was comparable to, and in most cases higher than, previous, face-to-face Familias Unidas interventions. High levels of baseline family stress were associated with lower initial engagement and lower family session participation. Greater parental Hispanicism was associated with more participation in eHealth parent group sessions and across the total intervention. Higher levels of baseline effective parenting, in other words less intervention need, were significantly associated with lower levels of total intervention participation and lower levels of family session participation. Implications for preventive interventions delivered via Internet are discussed.


Assuntos
Participação da Comunidade/tendências , Poder Familiar , Medicina Preventiva , Telemedicina , Adolescente , Comportamento do Adolescente , Relações Familiares , Feminino , Previsões , Hispânico ou Latino , Humanos , Masculino
8.
Prev Sci ; 19(Suppl 1): 74-94, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28013420

RESUMO

This paper presents the first findings of an integrative data analysis of individual-level data from 19 adolescent depression prevention trials (n = 5210) involving nine distinct interventions across 2 years post-randomization. In separate papers, several interventions have been found to decrease the risk of depressive disorders or elevated depressive/internalizing symptoms among youth. One type of intervention specifically targets youth without a depressive disorder who are at risk due to elevated depressive symptoms and/or having a parent with a depressive disorder. A second type of intervention targets two broad domains: prevention of problem behaviors, which we define as drug use/abuse, sexual risk behaviors, conduct disorder, or other externalizing problems, and general mental health. Most of these latter interventions improve parenting or family factors. We examined the shared and unique effects of these interventions by level of baseline youth depressive symptoms, sociodemographic characteristics of the youth (age, sex, parent education, and family income), type of intervention, and mode of intervention delivery to the youth, parent(s), or both. We harmonized eight different measures of depression utilized across these trials and used growth models to evaluate intervention impact over 2 years. We found a significant overall effect of these interventions on reducing depressive symptoms over 2 years and a stronger impact among those interventions that targeted depression specifically rather than problem behaviors or general mental health, especially when baseline symptoms were high. Implications for improving population-level impact are discussed.


Assuntos
Depressão/prevenção & controle , Promoção da Saúde , Adolescente , Terapia Cognitivo-Comportamental , Análise de Dados , Depressão/fisiopatologia , Feminino , Humanos , Masculino , Avaliação de Resultados em Cuidados de Saúde , Poder Familiar , Pais/educação
9.
Br J Psychiatry ; 218(5): 287-288, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-35048849
10.
Prev Sci ; 17(5): 595-605, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-27154768

RESUMO

Familias Unidas is a family-focused preventive intervention that has been found to reduce drug use and sexual risk behaviors among Hispanic adolescents. In some trials, Familias Unidas has also been found to be efficacious in reducing adolescent internalizing symptoms (i.e., depressive and anxiety symptoms), even though the intervention did not specifically target internalizing symptoms. This study examines potential mediators or mechanisms by which Familias Unidas influences internalizing symptoms, specifically the role of intervention-targeted improvements in parent-adolescent communication and reductions in youth externalizing behaviors. A total of 213 Hispanic eighth grade students with a history of externalizing behavior problems and their primary caregivers were recruited from the public school system. Participants, with a mean age of 13.8 years, were randomized into the Familias Unidas intervention or community practice control condition and assessed at baseline, 6, 18, and 30 months post-baseline. A cascading mediation model was tested in which the Familias Unidas intervention was hypothesized to decrease adolescent internalizing symptoms through two mediators: improvements in parent-adolescent communication leading to decreases in externalizing behaviors. Findings show that the intervention had significant direct effects on youth internalizing symptoms at 30 months post-baseline. In addition, the cascading mediation model was supported in which the Familias Unidas intervention predicted significant improvements in parent-adolescent communication at 6 months, subsequently decreasing externalizing behaviors at 18 months, and ultimately reducing youth internalizing symptoms at 30 months post-baseline. Implications for prevention interventions are discussed.


Assuntos
Hispânico ou Latino , Relações Pais-Filho , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Adolescente , Adulto , Feminino , Florida , Humanos , Masculino , Pessoa de Meia-Idade , Medição de Risco
11.
Prev Sci ; 17(6): 765-78, 2016 08.
Artigo em Inglês | MEDLINE | ID: mdl-27220838

RESUMO

Internet-connected devices are changing the way people live, work, and relate to one another. For prevention scientists, technological advances create opportunities to promote the welfare of human subjects and society. The challenge is to obtain the benefits while minimizing risks. In this article, we use the guiding principles for ethical human subjects research and proposed changes to the Common Rule regulations, as a basis for discussing selected opportunities and challenges that new technologies present for prevention science. The benefits of conducting research with new populations, and at new levels of integration into participants' daily lives, are presented along with five challenges along with technological and other solutions to strengthen the protections that we provide: (1) achieving adequate informed consent with procedures that are acceptable to participants in a digital age; (2) balancing opportunities for rapid development and broad reach, with gaining adequate understanding of population needs; (3) integrating data collection and intervention into participants' lives while minimizing intrusiveness and fatigue; (4) setting appropriate expectations for responding to safety and suicide concerns; and (5) safeguarding newly available streams of sensitive data. Our goal is to promote collaboration between prevention scientists, institutional review boards, and community members to safely and ethically harness advancing technologies to strengthen impact of prevention science.


Assuntos
Experimentação Humana/ética , Medicina Preventiva , Segurança , Tecnologia , Guias como Assunto , Política de Saúde , Experimentação Humana/legislação & jurisprudência , Humanos , Internet
12.
Fam Process ; 55(1): 91-106, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25683164

RESUMO

Familias Unidas is an intervention that has been found to be efficacious in preventing and reducing substance use, sexual risk, and problem behaviors among Hispanic youth. While it does not specifically target youth internalizing symptoms, the intervention works to strengthen parenting and family factors associated with reduced risk of internalizing symptoms (i.e., depression, anxiety symptoms). This study examines the effects of Familias Unidas on internalizing symptoms among high-risk youth, as well as the role of family level factors in the intervention's effects. A total of 242 12-17-year-old Hispanic youth with a history of delinquency and their primary caregivers were recruited from the school and juvenile justice systems, and randomly assigned to the Familias Unidas intervention or community practice control. A linear latent growth model was used to examine intervention effects on the trajectory of adolescent internalizing symptoms from baseline to 6 and 12 months post-baseline. Results show that the Familias Unidas intervention was more efficacious than control in reducing youth internalizing symptoms. Baseline youth externalizing and internalizing symptoms did not moderate the intervention's effects on the trajectory of youth internalizing symptoms. While parent-adolescent communication did not significantly moderate the intervention's effects, changes in parent-adolescent communication mediated the intervention's effects on internalizing symptoms, showing stronger intervention effects for youth starting with poorer communication. Findings indicate that the Familias Unidas intervention can reduce internalizing symptoms among high-risk Hispanic youth, and that improving parent-youth communication, a protective family factor, may be one of the mechanisms by which the intervention influences youth internalizing symptoms.


Assuntos
Ansiedade/prevenção & controle , Comunicação , Depressão/prevenção & controle , Terapia Familiar/métodos , Hispânico ou Latino/psicologia , Delinquência Juvenil , Adolescente , Criança , Depressão/psicologia , Feminino , Humanos , Masculino , Relações Pais-Filho , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Sexo sem Proteção/prevenção & controle
13.
Child Adolesc Ment Health ; 21(2): 109-114, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27346986

RESUMO

BACKGROUND: Literature suggests that physical activity (PA) and sedentary behavior may be associated with adolescent mental health symptoms. A gap in the literature is whether different types of PA have unique impacts on internalizing and externalizing symptoms. This study separately assesses the association of organized PA, unorganized PA, and sedentary behavior with internalizing and externalizing symptoms. METHOD: This study analyzed baseline data from a randomized controlled trial of a preventive intervention with 575 Hispanic adolescents. Using separate multivariable linear mixed models, the relationship between the independent variables of PA and sedentary behavior and the dependent variables of internalizing and externalizing symptoms was evaluated. RESULTS: Organized PA was not associated with internalizing or externalizing symptoms; however, higher levels of unorganized PA were associated with greater internalizing and externalizing symptoms. Increased sedentary behavior was also associated with higher levels of externalizing symptoms, but not internalizing symptoms. CONCLUSIONS: Implications of this study highlight the need to examine types of PA separately as they may differentially deferentially influence adolescent mental health symptoms. Potential explanations for these findings and suggested further analyses are discussed.

14.
Stat Methods Appt ; 25(4): 565-579, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28239330

RESUMO

Mediation analysis often requires larger sample sizes than main effect analysis to achieve the same statistical power. Combining results across similar trials may be the only practical option for increasing statistical power for mediation analysis in some situations. In this paper, we propose a method to estimate: 1) marginal means for mediation path a, the relation of the independent variable to the mediator; 2) marginal means for path b, the relation of the mediator to the outcome, across multiple trials; and 3) the between-trial level variance-covariance matrix based on a bivariate normal distribution. We present the statistical theory and an R computer program to combine regression coefficients from multiple trials to estimate a combined mediated effect and confidence interval under a random effects model. Values of coefficients a and b, along with their standard errors from each trial are the input for the method. This marginal likelihood based approach with Monte Carlo confidence intervals provides more accurate inference than the standard meta-analytic approach. We discuss computational issues, apply the method to two real-data examples and make recommendations for the use of the method in different settings.

15.
Prev Sci ; 16(5): 642-51, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25349137

RESUMO

Certain subgroups of youth are at high risk for depression and elevated depressive symptoms, and experience limited access to quality mental health care. Examples are socioeconomically disadvantaged, racial/ethnic minority, and sexual minority youth. Research shows that there are efficacious interventions to prevent youth depression and depressive symptoms. These preventive interventions have the potential to play a key role in addressing these mental health disparities by reducing youth risk factors and enhancing protective factors. However, there are comparatively few preventive interventions directed specifically to these vulnerable subgroups, and sample sizes of diverse subgroups in general prevention trials are often too low to assess whether preventive interventions work equally well for vulnerable youth compared to other youth. In this paper, we describe the importance and need for "scientific equity," or equality and fairness in the amount of scientific knowledge produced to understand the potential solutions to such health disparities. We highlight possible strategies for promoting scientific equity, including the following: increasing the number of prevention research participants from vulnerable subgroups, conducting more data synthesis analyses and implementation science research, disseminating preventive interventions that are efficacious for vulnerable youth, and increasing the diversity of the prevention science research workforce. These strategies can increase the availability of research evidence to determine the degree to which preventive interventions can help address mental health disparities. Although this paper utilizes the prevention of youth depression as an illustrative case example, the concepts are applicable to other health outcomes for which there are disparities, such as substance use and obesity.


Assuntos
Depressão/etnologia , Depressão/prevenção & controle , Transtorno Depressivo/etnologia , Transtorno Depressivo/prevenção & controle , Etnicidade/psicologia , Etnicidade/estatística & dados numéricos , Disparidades em Assistência à Saúde/etnologia , Populações Vulneráveis/etnologia , Populações Vulneráveis/estatística & dados numéricos , Adolescente , Estudos Transversais , Diversidade Cultural , Depressão/epidemiologia , Transtorno Depressivo/epidemiologia , Feminino , Pesquisa sobre Serviços de Saúde/estatística & dados numéricos , Disparidades em Assistência à Saúde/estatística & dados numéricos , Humanos , Masculino , Ensaios Clínicos Controlados Aleatórios como Assunto/estatística & dados numéricos , Apoio à Pesquisa como Assunto/estatística & dados numéricos , Fatores de Risco , Estados Unidos
16.
Prev Sci ; 15(6): 917-28, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24390684

RESUMO

Studies document that there are efficacious interventions to prevent adolescent depression and internalizing symptoms, including several family-focused interventions. Questions remain about for whom interventions work (moderation) and by what mechanisms they work (mediation) to prevent internalizing symptoms. Unfortunately, single trials are often underpowered to address moderation and mediation, an issue addressed in this paper. This synthesis study combined individual-level, longitudinal data from 721 adolescents across 3 randomized clinical trials of Familias Unidas, a family-focused prevention intervention for Hispanic youth. Using integrative data analysis (IDA) methods applied to trials, the study examined intervention moderation and mediation effects on internalizing symptoms. Baseline internalizing symptoms were a significant moderator of the intervention's effects on internalizing symptoms, while baseline externalizing symptoms did not moderate intervention effects. Baseline parent-adolescent communication, a modifiable risk factor and hypothesized mechanism by which the intervention works, significantly moderated the intervention's effects. Specifically, the intervention was more efficacious in its impact on internalizing symptoms for youth with lower initial levels of parent-adolescent communication compared to those with higher communication levels. Moderated mediation analyses showed that parent-adolescent communication changes mediated the intervention's effects on internalizing symptoms, with stronger effects for those with poorer baseline communication. Results suggest a potential benefit of identifying youth risks prior to interventions, and targeting specific modifiable mediators that lead to reductions of internalizing problems of adolescents. Findings also highlight advantages of utilizing data from combined trials and IDA for examining intervention moderators and mediators.


Assuntos
Depressão/etnologia , Hispânico ou Latino/psicologia , Relações Pais-Filho/etnologia , Adolescente , Lista de Checagem , Interpretação Estatística de Dados , Depressão/prevenção & controle , Feminino , Humanos , Estudos Longitudinais , Masculino , Ensaios Clínicos Controlados Aleatórios como Assunto , Análise de Regressão
17.
Br J Nutr ; 110(5): 901-10, 2013 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-23340203

RESUMO

Few studies have evaluated the effects of alcohol consumption on the incidence of the metabolic syndrome (MetS). Therefore, the objective of the present study was to examine the association between alcohol consumption and incident MetS in a population of US men. This is a prospective study of 7483 Caucasian men, who were free of the MetS and CVD at baseline. Information was collected on alcohol consumption, health status and fitness level at an initial clinical examination. Additional health information and determination of incident cases of the MetS were obtained at follow-up clinical examinations between 1979 and 2005. Compared with non-drinkers, the multivariate hazard ratios of the MetS for light (1-3 drinks/week), moderate (4-7 drinks/week), moderate-heavy (8-13 drinks/week) and heavy ( ≥ 14 drinks/week) drinkers were 0.81 (95 % CI 0.68, 0.95), 0.68 (95 % CI 0.57, 0.80), 0.70 (95 % CI 0.59, 0.83) and 0.78 (95 % CI 0.66, 0.91), respectively. This association was seen across age groups, in men with one or more pre-existing MetS risk factors, and those with BMI ≥ 25 kg/m2, and in all alcohol beverage types at most levels of alcohol consumption. An inverse dose-response association between alcohol consumption and low HDL concentrations was observed, while significant associations were observed between high fasting glucose concentrations and moderate, moderate-heavy and heavy levels of alcohol consumption. Alcohol consumption was not significantly associated with central obesity, hypertriacylglycerolaemia or hypertension. All levels of alcohol consumption provided significant inverse associations with incidence of the MetS. In particular, this effect was observed in overweight and/or obese individuals, in those who had pre-existing risk factors for the MetS, and extended across all types of alcoholic beverages consumed.


Assuntos
Consumo de Bebidas Alcoólicas/efeitos adversos , Síndrome Metabólica/epidemiologia , Síndrome Metabólica/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estudos Prospectivos , Fatores de Risco , Estados Unidos/epidemiologia , Adulto Jovem
18.
Prev Sci ; 14(2): 144-56, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21360061

RESUMO

This paper presents new methods for synthesizing results from subgroup and moderation analyses across different randomized trials. We demonstrate that such a synthesis generally results in additional power to detect significant moderation findings above what one would find in a single trial. Three general methods for conducting synthesis analyses are discussed, with two methods, integrative data analysis and parallel analyses, sharing a large advantage over traditional methods available in meta-analysis. We present a broad class of analytic models to examine moderation effects across trials that can be used to assess their overall effect and explain sources of heterogeneity, and present ways to disentangle differences across trials due to individual differences, contextual level differences, intervention, and trial design.


Assuntos
Variações Dependentes do Observador , Ensaios Clínicos Controlados Aleatórios como Assunto
19.
J Fam Psychol ; 37(1): 105-109, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36342424

RESUMO

Early-life alcohol use raises the risk of poor long-term alcohol and other health outcomes. U.S. Hispanics are less likely to access treatment if they develop alcohol abuse or dependence, making preventive interventions critical. Familias Unidas is a family-based intervention effective in preventing drug and sexual risk behavior among Hispanic youth. The effects of this intervention specifically on youth alcohol use have been less consistent and may be affected by parental factors. The intervention is primarily delivered to parents to ultimately reduce youth risk behaviors, applying research on protective parenting and family influences, such as parental monitoring and positive communication. This study conducted secondary data analysis of an effectiveness randomized controlled trial of the Familias Unidas intervention, examining parent moderators of intervention effects on adolescent alcohol use. A total of 746 Hispanic families with 12-16-year-old adolescents were randomized to intervention or control. Logistic regression analyses confirmed no evidence of intervention effectiveness in reducing 90-day adolescent alcohol use at 30-month follow-up. However, there was evidence that parent misuse moderated intervention effects on adolescent alcohol use. Among youth whose parents reported any episode of alcohol misuse in their lifetime, the intervention was associated with lower odds of youth alcohol use at 30 months compared to youth in the control condition. Potential reasons and intervention implications are reviewed, including how parent alcohol use experiences might raise awareness of youth risks and motivate involvement or protective behaviors. Understanding intervention moderators can help shape, target, and adapt interventions to enhance their effectiveness and reach. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Assuntos
Alcoolismo , Humanos , Adolescente , Criança , Pais , Poder Familiar , Comportamento Sexual , Hispânico ou Latino/psicologia
20.
Front Public Health ; 11: 1269840, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38054066

RESUMO

Introduction: Complex and continuous developments in health and healthcare require innovative changes in programs that educate public health scientists and professionals. Public health change agents need critical competencies to confront today and tomorrow's leading problems including leadership, communication, interprofessional practice, and systems thinking. The context challenges in public health education: Public Health training programs teach competencies through their applied field experience and culminating project, typically late in the program, and often implemented in isolation from peers and faculty. Objectives and skills do not always align closely with community-based program needs. Students pursuing a degree in science in public health need to deeply comprehend multi-dimensional and interconnected systemic problems and communicate with diverse stakeholders across disciplines to produce relevant community-engaged research. The University of Miami Public Health Learning Collaboratory (LC) was established to transform the learning experience of public health master's students by providing opportunities to develop necessary core skills for effective public health practice early in their training, while applying these skills to address real-world public health needs in the community. The Learning Collaboratory structure pedagogical approach and programmatic details: Spanning an average of 3 semesters, the LC promotes student involvement in collaborative and impactful capstone and thesis projects. Practice-based teaching and service learning are central approaches to teaching cross-cutting competencies of leadership, communication, problem solving, collaboration, and systems thinking in public health. Significant to the approach is the engagement of previous cohorts of senior students to teach back to junior students, further integrating concepts learned. Long term alumni feedback recognized strengths of the program, including its structure, teamwork & collaboration, critical thinking & problem solving, guidance, nurture & support, teaching back, and content & curriculum. Community partners agreed the LC prepared students to practice in the field of public health. Discussion: The LC is a promising model for master's level public health education and community application, given the opportunities it provides to strengthen and integrate students' public health skills in a supportive environment, and enhance the transferability and sustainability of student and faculty's community public health work.


Assuntos
Saúde Pública , Estudantes de Saúde Pública , Humanos , Aprendizagem , Currículo , Educação em Saúde
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