Detalhe da pesquisa
1.
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase.
J Biol Chem
; 298(2): 101531, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953855
2.
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens.
Eur J Med Chem
; 264: 115971, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38071795
3.
Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity.
Metabolites
; 13(2)2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36837770
4.
Convergent synthesis of conjugated 1,2-disubstituted E-allylic alcohols from two aldehydes and methylenetriphenylphosphorane.
Org Biomol Chem
; 10(39): 7949-51, 2012 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22936294
5.
Alkenes from ß-lithiooxyphosphonium ylides generated by trapping α-lithiated terminal epoxides with triphenylphosphine.
Beilstein J Org Chem
; 8: 1896-900, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209528
6.
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.
Cell Chem Biol
; 29(5): 870-882.e11, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520745