1.
J Appl Genet
; 42(3): 351-8, 2001.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14564041
RESUMO
MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) is a disease mainly due to a mutation at position 3243 (A --> G) in the leucine tRNA gene in mitochondrial DNA. Symptoms of the disorder are complex and the exact pathogenesis is not understood. A review of the literature on the subject is presented.
2.