Detalhe da pesquisa
1.
Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape.
PLoS Comput Biol
; 16(8): e1008041, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32745136
2.
Targeting Cellular DNA Damage Responses in Cancer: An In Vitro-Calibrated Agent-Based Model Simulating Monolayer and Spheroid Treatment Responses to ATR-Inhibiting Drugs.
Bull Math Biol
; 83(10): 103, 2021 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34459993
3.
What does not kill a tumour may make it stronger: In silico insights into chemotherapeutic drug resistance.
J Theor Biol
; 454: 253-267, 2018 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29909142
4.
Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model.
J Theor Biol
; 446: 87-100, 2018 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29524441
5.
Systems oncology: towards patient-specific treatment regimes informed by multiscale mathematical modelling.
Semin Cancer Biol
; 30: 13-20, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24607841
6.
Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments.
J Theor Biol
; 401: 1-14, 2016 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27084360
7.
Towards predicting the response of a solid tumour to chemotherapy and radiotherapy treatments: clinical insights from a computational model.
PLoS Comput Biol
; 9(7): e1003120, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23874170
8.
Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model.
J Theor Biol
; 308: 1-19, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22659352
9.
Development of a coupled simulation toolkit for computational radiation biology based on Geant4 and CompuCell3D.
Phys Med Biol
; 66(4): 045026, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33339019
10.
Blackboard to Bedside: A Mathematical Modeling Bottom-Up Approach Toward Personalized Cancer Treatments.
JCO Clin Cancer Inform
; 3: 1-11, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742485
11.
Role of hypoxia-activated prodrugs in combination with radiation therapy: An in silico approach.
Math Biosci Eng
; 16(6): 6257-6273, 2019 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31698561