Detalhe da pesquisa
1.
Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.
Nature
; 606(7912): 120-128, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545678
2.
Genome-wide enhancer maps link risk variants to disease genes.
Nature
; 593(7858): 238-243, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33828297
3.
Leveraging gene co-regulation to identify gene sets enriched for disease heritability.
Am J Hum Genet
; 109(3): 393-404, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108496
4.
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations.
Nature
; 559(7714): 350-355, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29995854
5.
Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.
Hum Mol Genet
; 30(16): 1521-1534, 2021 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33987664
6.
Dissecting the genetics of complex traits using summary association statistics.
Nat Rev Genet
; 18(2): 117-127, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27840428
7.
Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.
Hum Mol Genet
; 29(7): 1057-1067, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595288
8.
Disease Heritability Enrichment of Regulatory Elements Is Concentrated in Elements with Ancient Sequence Age and Conserved Function across Species.
Am J Hum Genet
; 104(4): 611-624, 2019 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905396
9.
Extreme Polygenicity of Complex Traits Is Explained by Negative Selection.
Am J Hum Genet
; 105(3): 456-476, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402091
10.
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
Am J Hum Genet
; 104(1): 65-75, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595370
11.
IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.
Am J Hum Genet
; 104(5): 879-895, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006511
12.
Genes with High Network Connectivity Are Enriched for Disease Heritability.
Am J Hum Genet
; 104(5): 896-913, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051114
13.
Estimating cross-population genetic correlations of causal effect sizes.
Genet Epidemiol
; 43(2): 180-188, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30474154
14.
Mixed Model Association with Family-Biased Case-Control Ascertainment.
Am J Hum Genet
; 100(1): 31-39, 2017 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28017371
15.
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues.
Am J Hum Genet
; 100(4): 605-616, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28343628
16.
Transethnic Genetic-Correlation Estimates from Summary Statistics.
Am J Hum Genet
; 99(1): 76-88, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27321947
17.
Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure.
Am J Hum Genet
; 99(5): 1130-1139, 2016 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27773431
18.
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia.
Am J Hum Genet
; 98(3): 456-472, 2016 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924531
19.
Pitfalls of predicting complex traits from SNPs.
Nat Rev Genet
; 14(7): 507-15, 2013 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23774735
20.
Multiethnic polygenic risk scores improve risk prediction in diverse populations.
Genet Epidemiol
; 41(8): 811-823, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110330