Detalhe da pesquisa
1.
Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1 -acetylcholine receptor agonist: A randomized cross-over trial.
Br J Clin Pharmacol
; 87(11): 4439-4449, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891333
2.
First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M1 -receptor partial agonist for the treatment of dementias.
Br J Clin Pharmacol
; 87(7): 2945-2955, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351971
3.
Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals.
Int J Mol Sci
; 21(9)2020 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365768
4.
Reversal of mecamylamine-induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses.
Br J Clin Pharmacol
; 84(5): 888-899, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29319910
5.
Usefulness of Plasma Amyloid as a Prescreener for the Earliest Alzheimer Pathological Changes Depends on the Study Population.
Ann Neurol
; 87(1): 154-155, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31675127
6.
Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.
J Neurol Sci
; 449: 120658, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37079973
7.
Inflammatory plasma biomarkers in subjects with preclinical Alzheimer's disease.
Alzheimers Res Ther
; 14(1): 106, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35922871
8.
A cross-sectional study in healthy elderly subjects aimed at development of an algorithm to increase identification of Alzheimer pathology for the purpose of clinical trial participation.
Alzheimers Res Ther
; 13(1): 132, 2021 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274005
9.
Detection of Clenbuterol-Induced Changes in Heart Rate Using At-Home Recorded Smartwatch Data: Randomized Controlled Trial.
JMIR Form Res
; 5(12): e31890, 2021 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34967757
10.
A Validated Novel Tool for Capturing Faculty-Student Joint Behaviors with the COPUS Instrument.
J Microbiol Biol Educ
; 20(3)2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31890081
11.
An EEG nicotinic acetylcholine index to assess the efficacy of pro-cognitive compounds.
Clin Neurophysiol
; 129(11): 2325-2332, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248622