Detalhe da pesquisa
1.
Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D3 kinetics for extrapolation from mouse to man: Commentary.
Biopharm Drug Dispos
; 41(3): 126-148, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32319119
2.
Highlighting Vitamin D Receptor-Targeted Activities of 1α,25-Dihydroxyvitamin D3 in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling.
Drug Metab Dispos
; 46(1): 75-87, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084783
3.
Potencies of vitamin D analogs, 1α-hydroxyvitamin D3 , 1α-hydroxyvitamin D2 and 25-hydroxyvitamin D3 , in lowering cholesterol in hypercholesterolemic mice in vivo.
Biopharm Drug Dispos
; 39(4): 196-204, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29488238
4.
Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.
Biopharm Drug Dispos
; 39(2): 99-115, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29243851
5.
Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models.
J Pharmacol Exp Ther
; 360(1): 174-191, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789682
6.
Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice.
Drug Metab Dispos
; 44(2): 189-208, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586377
7.
Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters.
Drug Metab Dispos
; 44(9): 1524-35, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27342868
8.
Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Gastroenterology
; 146(4): 1048-59, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24365583
9.
Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.
Am J Physiol Endocrinol Metab
; 304(9): E977-89, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23482451
10.
Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters.
AAPS J
; 24(4): 71, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35650371
11.
PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.
Br J Pharmacol
; 172(14): 3611-26, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829051
12.
Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.
J Pharm Sci
; 103(11): 3793-3805, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25266751