Detalhe da pesquisa
1.
Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [18F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease.
Molecules
; 28(20)2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894622
2.
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.
Bioorg Med Chem
; 28(1): 115195, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31761726
3.
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.
Bioorg Med Chem
; 27(1): 55-64, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446439
4.
Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES.
J Biol Chem
; 291(6): 2556-65, 2016 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26555264
5.
Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors.
ChemMedChem
; 18(21): e202100406, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486233
6.
Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors.
J Med Chem
; 64(9): 5956-5972, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900772
7.
Conformational gating, dynamics and allostery in human monoacylglycerol lipase.
Sci Rep
; 10(1): 18531, 2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116203
8.
Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase.
Sci Rep
; 8(1): 1719, 2018 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29379013
9.
A comparison of novel, selective fatty acid amide hydrolase (FAAH), monoacyglycerol lipase (MAGL) or dual FAAH/MAGL inhibitors to suppress acute and anticipatory nausea in rat models.
Psychopharmacology (Berl)
; 233(12): 2265-75, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048155
10.
Probing the carboxyester side chain in controlled deactivation (-)-δ(8)-tetrahydrocannabinols.
J Med Chem
; 58(2): 665-81, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25470070