Detalhe da pesquisa
1.
Atomic resolution structure of full-length human insulin fibrils.
Proc Natl Acad Sci U S A
; 121(23): e2401458121, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38809711
2.
Liquid-liquid phase separation of amyloid-ß oligomers modulates amyloid fibrils formation.
J Biol Chem
; 299(3): 102926, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682493
3.
Structural Insights into Seeding Mechanisms of hIAPP Fibril Formation.
J Am Chem Soc
; 146(20): 13783-13796, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38723619
4.
Aggregation mechanisms and molecular structures of amyloid-ß in Alzheimer's disease.
Chemistry
; : e202400277, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38888453
5.
Deuteration for High-Resolution Detection of Protons in Protein Magic Angle Spinning (MAS) Solid-State NMR.
Chem Rev
; 122(10): 10019-10035, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34870415
6.
Sensitivity-Enhanced Multidimensional Solid-State NMR Spectroscopy by Optimal-Control-Based Transverse Mixing Sequences.
J Am Chem Soc
; 144(38): 17336-17340, 2022 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36074981
7.
Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability.
J Biol Chem
; 295(52): 18474-18484, 2020 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093170
8.
Mapping the Binding Interface of PET Tracer Molecules and Alzheimer Disease Aß Fibrils by Using MAS Solid-State NMR Spectroscopy.
Chembiochem
; 21(17): 2495-2502, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32291951
9.
Structural Insight into IAPP-Derived Amyloid Inhibitors and Their Mechanism of Action.
Angew Chem Int Ed Engl
; 59(14): 5771-5781, 2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31863711
10.
A single residue switch reveals principles of antibody domain integrity.
J Biol Chem
; 293(44): 17107-17118, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228183
11.
Determination of methyl order parameters using solid state NMR under off magic angle spinning.
J Biomol NMR
; 73(8-9): 471-475, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31407204
12.
MAS dependent sensitivity of different isotopomers in selectively methyl protonated protein samples in solid state NMR.
J Biomol NMR
; 73(10-11): 625-631, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515660
13.
Accurate Determination of 1 H-15 N Dipolar Couplings Using Inaccurate Settings of the Magic Angle in Solid-State NMR Spectroscopy.
Angew Chem Int Ed Engl
; 58(13): 4286-4290, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30694593
14.
Overcoming Volume Selectivity of Dipolar Recoupling in Biological Solid-State NMR Spectroscopy.
Angew Chem Int Ed Engl
; 57(44): 14514-14518, 2018 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29989288
15.
Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-ß Peptide Which Exhibit Reduced Neurotoxicity.
Biochemistry
; 55(12): 1839-49, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900939
16.
Structural Mechanism of the Interaction of Alzheimer Disease Aß Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide.
J Biol Chem
; 290(48): 28737-45, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416887
17.
Immobilization of soluble protein complexes in MAS solid-state NMR: Sedimentation versus viscosity.
Solid State Nucl Magn Reson
; 76-77: 7-14, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017576
18.
A residue-specific shift in stability and amyloidogenicity of antibody variable domains.
J Biol Chem
; 289(39): 26829-26846, 2014 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25096580
19.
Access to Cα backbone dynamics of biological solids by 13C T1 relaxation and molecular dynamics simulation.
J Am Chem Soc
; 137(3): 1094-100, 2015 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564702
20.
Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization.
J Biomol NMR
; 61(2): 151-60, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25634300