Detalhe da pesquisa
1.
Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation.
Chem Rev
; 122(1): 269-339, 2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34677059
2.
TGFß drives immune evasion in genetically reconstituted colon cancer metastasis.
Nature
; 554(7693): 538-543, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443964
3.
Cyclometallated Imides as Templates for the H-Bond Directed Iridium-Catalyzed Asymmetric Hydrogenation of N-Methyl, N-Alkyl and N-Aryl Imines.
Angew Chem Int Ed Engl
; : e202404955, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38639173
4.
Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders.
Angew Chem Int Ed Engl
; 63(12): e202316730, 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38153885
5.
Iridium-Catalyzed Asymmetric Hydrogenation of 2,3-Diarylallyl Amines with a Threonine-Derived P-Stereogenic Ligand for the Synthesis of Tetrahydroquinolines and Tetrahydroisoquinolines.
Angew Chem Int Ed Engl
; 61(29): e202204300, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35543384
6.
P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis.
Acc Chem Res
; 53(3): 676-689, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105437
7.
Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions.
Bioconjug Chem
; 31(3): 933-938, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32057238
8.
TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-ß signaling.
Nucleic Acids Res
; 46(17): 9220-9235, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30060237
9.
Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols.
Angew Chem Int Ed Engl
; 59(19): 7521-7527, 2020 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31981390
10.
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst.
J Am Chem Soc
; 140(49): 16967-16970, 2018 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30475609
11.
P-Stereogenic and Non-P-Stereogenic Ir-MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles.
J Org Chem
; 83(8): 4618-4627, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29616810
12.
Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands.
J Org Chem
; 82(13): 7065-7069, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640640
13.
Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates.
Angew Chem Int Ed Engl
; 56(28): 8206-8210, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28603882
14.
An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomized Controlled Trial.
J Med Internet Res
; 18(8): e231, 2016 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27565118
15.
Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides.
Angew Chem Int Ed Engl
; 55(28): 7988-92, 2016 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27186653
16.
Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 4): 844-53, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849395
17.
Addition of HOBt improves the conversion of thioester-Amine chemical ligation.
Biopolymers
; 104(6): 693-702, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396113
18.
Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors.
Org Biomol Chem
; 13(23): 6500-10, 2015 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975710
19.
Regioselectivity of intermolecular Pauson-Khand reaction of aliphatic alkynes: experimental and theoretical study of the effect of alkyne polarization.
J Org Chem
; 79(22): 10999-1010, 2014 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25321602
20.
A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.
Bioorg Med Chem Lett
; 24(1): 103-7, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24342240