Detalhe da pesquisa
1.
Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations.
Mem Inst Oswaldo Cruz
; 113(9): e180162, 2018 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30066751
2.
Knockdown of Host Antioxidant Defense Genes Enhances the Effect of Glucantime on Intracellular Leishmania braziliensis in Human Macrophages.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28461312
3.
Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification.
Bioorg Med Chem
; 25(6): 1889-1900, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215783
4.
Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity.
Molecules
; 21(10)2016 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27735872
5.
Upregulation of Cysteine Synthase and Cystathionine ß-Synthase Contributes to Leishmania braziliensis Survival under Oxidative Stress.
Antimicrob Agents Chemother
; 59(8): 4770-81, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26033728
6.
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.
Antimicrob Agents Chemother
; 59(5): 2666-77, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25712353
7.
Molecular characterization of Cyclophilin (TcCyP19) in Trypanosoma cruzi populations susceptible and resistant to benznidazole.
Exp Parasitol
; 148: 73-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450774
8.
In vitro activity of 1,3-bisaryloxypropanamines against Trypanosoma cruzi-infected L929 cultures.
Mem Inst Oswaldo Cruz
; 110(4): 566-8, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061148
9.
Bioactive endophytic fungi isolated from Caesalpinia echinata Lam. (Brazilwood) and identification of beauvericin as a trypanocidal metabolite from Fusarium sp.
Mem Inst Oswaldo Cruz
; 110(1): 65-74, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25742265
10.
In vitro interaction between paromomycin sulphate and four drugs with leishmanicidal activity against three New World Leishmania species.
J Antimicrob Chemother
; 69(1): 150-4, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23970484
11.
The in vitro activity of fatty diamines and amino alcohols against mixed amastigote and trypomastigote Trypanosoma cruzi forms.
Mem Inst Oswaldo Cruz
; 109(3): 362-4, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24831550
12.
The level of ascorbate peroxidase is enhanced in benznidazole-resistant populations of Trypanosoma cruzi and its expression is modulated by stress generated by hydrogen peroxide.
Mem Inst Oswaldo Cruz
; 107(4): 494-502, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22666860
13.
Hb Stanleyville-II [α78(EF7)AsnâLys (α2); HbA2: c.237C>A]: incidence of 1:11,500 in a newborn screening program in Brazil.
Hemoglobin
; 36(4): 388-94, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22625430
14.
In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
J Antimicrob Chemother
; 66(6): 1295-7, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478242
15.
The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil.
Mem Inst Oswaldo Cruz
; 106(4): 475-8, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739037
16.
The activity of a metronidazole analogue and its ß-cyclodextrin complex against Trypanosoma cruzi.
Mem Inst Oswaldo Cruz
; 106(8): 1055-7, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22241134
17.
Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Antimicrob Agents Chemother
; 54(7): 2940-52, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457822
18.
Susceptibility of Triatoma brasiliensis from state of Ceará, Northeastern Brazil, to the pyrethroid deltamethrin.
Mem Inst Oswaldo Cruz
; 105(3): 348-52, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20512253
19.
CA88, a nuclear repetitive DNA sequence identified in Schistosoma mansoni, aids in the genotyping of nine Schistosoma species of medical and veterinary importance.
Mem Inst Oswaldo Cruz
; 105(4): 391-7, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20721481
20.
The anticancer drug tamoxifen is active against Trypanosoma cruzi in vitro but ineffective in the treatment of the acute phase of Chagas disease in mice.
Mem Inst Oswaldo Cruz
; 105(7): 945-8, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21120371