Evidence of Validity of the Autism Mental Status Examination (AMSE) in a Brazilian Sample.

This study investigated the psychometric properties of the Autism Mental Status Examination (AMSE) in a Brazilian sample of children and adolescents with autism spectrum disorder (ASD). A sample of 260 children and adolescents, comprising 56 (21.5%) females and 204 (78.5%) males, was assessed. The participants were submitted to both the childhood autism rating scale (CARS-BR) and the AMSE. The CARS-BR was used to estimate ASD severity and the cutoff point on the AMSE. Spearman's correlation test was employed to determine the correlation between the AMSE and CARS-BR scales. The cutoff values were calculated using the ROC (receiver operating characteristic) curve, identifying the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). The homogeneity of the items of the AMSE was determined using Cronbach´s alpha. The AMSE exhibited good internal consistency (0.74), sensitivity (0.91) and specificity (0.98); and high correlation with the CARS-BR (ρ = 0.91, p < 0.01). Preliminary results showed that the AMSE is a tool with good psychometric properties for ASD screening.

Fibroadenoma da vulva: relato de dois casos / Fibroadenoma of the vulva: a report of two cases

O fibroadenoma é definido como lesão nodular benigna e freqüente em mamas de mulheres jovens. No entanto, existem alguns relatos de sua localização fora do tecido mamário. Quando encontrado em região vulvar, existe divergência quanto à sua origem. Há controvérsia entre os autores que consideram que a lesão poderia ser proveniente de tecido mamário ectópico e aqueles que acreditam na origem no interior das glândulas sudoríparas ano-genitais, que mimetizariam o tecido glandular mamário. Este artigo relata dois casos de fibroadenoma em região vulvar, em uma mulher de 26 anos e outra de 27 anos, ambas com presença de lesão nodular circunscrita em região de grandes lábios, submetidas à exérese cirúrgica para confirmação histopatológica. Os conceitos sobre a histogênese são discutidos. O artigo chama a atenção para a possibilidade de ocorrência dessa lesão, freqüentemente incontrada na mama, mas que pode ser observada em outra localização

Fibroadenoma is defined as a nodular, benign and not uncommon lesion found in the mammary tissue of young women. However, there are some reports of fibroadenomas occurring in other tissues. When present in the vulvar region, there are divergences regarding its origin. There is a controversy between authors who believe that the lesion originated from ectopic mammary tissue and those who believe that it originated inside the anal-genital sweat glands, which mimic mammary gland tissue. This article reports two cases of fibroadenomas in the vulvar region, one in a 26-year-old woman and the other in a 27-year-old woman. They both presented circumscribed nodular lesion in the labia majora region and were submitted to surgical excision to confirm histopathology. Histogenesis concepts are discussed. The article emphasizes the possibility of this lesion occurring in areas other than mammary tissue