1.
Org Lett
; 19(22): 6064-6067, 2017 11 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29095633
RESUMO
A copper-catalyzed site-selective propargylation/allenylation reaction toward carbonyl compounds has been mechanistically investigated using a computational approach. Different reaction pathways and catalytic cycles were investigated. Control of the site selectivity arises from a destabilizing interaction introduced by the phenyl-substituted ligand.