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1.
Child Dev ; 88(5): 1615-1628, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28128457

RESUMO

A nap soon after encoding leads to better learning in infancy. However, whether napping plays the same role in preschoolers' learning is unclear. In Experiment 1 (N = 39), 3-year-old habitual and nonhabitual nappers learned novel verbs before a nap or a period of wakefulness and received a generalization test examining word extension to novel actors after 24 hr. Only habitual and nonhabitual nappers who napped after learning generalized 24 hr later. In Experiment 2 (N = 40), children learned the same verbs but were tested within 2-3 min of training. Here, habitual and nonhabitual nappers retained the mappings but did not generalize. The results suggest that naps consolidate weak learning that habitual and nonhabitual nappers would otherwise forget over periods of wakefulness.


Assuntos
Desenvolvimento Infantil/fisiologia , Generalização Psicológica/fisiologia , Sono/fisiologia , Vigília/fisiologia , Pré-Escolar , Feminino , Humanos , Masculino
2.
Emerg Infect Dis ; 21(7): 1128-34, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26079176

RESUMO

In May 2014, a traveler from the Kingdom of Saudi Arabia was the first person identified with Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States. To evaluate transmission risk, we determined the type, duration, and frequency of patient contact among health care personnel (HCP), household, and community contacts by using standard questionnaires and, for HCP, global positioning system (GPS) tracer tag logs. Respiratory and serum samples from all contacts were tested for MERS-CoV. Of 61 identified contacts, 56 were interviewed. HCP exposures occurred most frequently in the emergency department (69%) and among nurses (47%); some HCP had contact with respiratory secretions. Household and community contacts had brief contact (e.g., hugging). All laboratory test results were negative for MERS-CoV. This contact investigation found no secondary cases, despite case-patient contact by 61 persons, and provides useful information about MERS-CoV transmission risk. Compared with GPS tracer tag recordings, self-reported contact may not be as accurate.


Assuntos
Infecções por Coronavirus/transmissão , Coronavírus da Síndrome Respiratória do Oriente Médio , Adulto , Busca de Comunicante , Infecções por Coronavirus/virologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição de Risco , Estados Unidos , Adulto Jovem
3.
MMWR Morb Mortal Wkly Rep ; 64(16): 443-4, 2015 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-25928470

RESUMO

On January 23, 2015, the Indiana State Department of Health (ISDH) began an ongoing investigation of an outbreak of human immunodeficiency virus (HIV) infection, after Indiana disease intervention specialists reported 11 confirmed HIV cases traced to a rural county in southeastern Indiana. Historically, fewer than five cases of HIV infection have been reported annually in this county. The majority of cases were in residents of the same community and were linked to syringe-sharing partners injecting the prescription opioid oxymorphone (a powerful oral semi-synthetic opioid analgesic). As of April 21, ISDH had diagnosed HIV infection in 135 persons (129 with confirmed HIV infection and six with preliminarily positive results from rapid HIV testing that were pending confirmatory testing) in a community of 4,200 persons.


Assuntos
Coinfecção/epidemiologia , Surtos de Doenças , Infecções por HIV/epidemiologia , Oximorfona/administração & dosagem , Abuso de Substâncias por Via Intravenosa/epidemiologia , Adolescente , Adulto , Causalidade , Comorbidade , Feminino , Hepatite C/epidemiologia , Heroína/administração & dosagem , Humanos , Indiana/epidemiologia , Masculino , Metenamina/administração & dosagem , Pessoa de Meia-Idade , Gravidez , Complicações Infecciosas na Gravidez/epidemiologia , População Rural , Parceiros Sexuais , Adulto Jovem
4.
Lang Speech Hear Serv Sch ; 49(1): 72-84, 2018 01 09.
Artigo em Inglês | MEDLINE | ID: mdl-29131888

RESUMO

Purpose: Variability in the input plays an important role in language learning. The current study examined the role of object variability for new word learning by preschoolers with specific language impairment (SLI). Method: Eighteen 4- and 5-year-old children with SLI were taught 8 new words in 3 short activities over the course of 3 sessions. Half of the children saw 3 identical objects corresponding to each new word during training (No Variability group); the other half of the children saw 3 different objects corresponding to each new word during training (High Variability group). Children completed vocabulary learning tests for objects seen during training and for new within-category objects that were never seen during training as a test of category generalization. Learning was assessed the day after each training activity, and retention was assessed 3 weeks after the last training session. Results: There were no group differences on trained or generalization items immediately following training sessions. However, children in the High Variability group demonstrated significantly better retention 3 weeks after experimental training. Conclusion: These findings demonstrate that object variability facilitates retention of new word learning by children with SLI. Supplemental Material: https://doi.org/10.23641/asha.5583979.


Assuntos
Transtornos do Desenvolvimento da Linguagem/psicologia , Rememoração Mental , Aprendizagem Verbal , Pré-Escolar , Feminino , Humanos , Desenvolvimento da Linguagem , Transtornos do Desenvolvimento da Linguagem/terapia , Testes de Linguagem , Masculino , Semântica , Materiais de Ensino , Vocabulário
5.
Neuroimage Clin ; 14: 277-285, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28203531

RESUMO

Individuals with developmental language impairment can show deficits into adulthood. This suggests that neural networks related to their language do not normalize with time. We examined the ability of 16 adults with and without impaired language to learn individual words in an unfamiliar language. Adults with impaired language were able to segment individual words from running speech, but needed more time to do so than their normal-language peers. ICA analysis of fMRI data indicated that adults with language impairment activate a neural network that is comparable to that of adults with normal language. However, a regional analysis indicated relative hyperactivation of a collection of regions associated with language processing. These results are discussed with reference to the Statistical Learning Framework and the sub-skills thought to relate to word segmentation.


Assuntos
Encéfalo/diagnóstico por imagem , Transtornos do Desenvolvimento da Linguagem/diagnóstico por imagem , Imageamento por Ressonância Magnética , Aprendizagem Verbal/fisiologia , Estimulação Acústica , Adolescente , Análise de Variância , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Masculino , Oxigênio/sangue , Adulto Jovem
6.
Front Psychol ; 8: 1234, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28798703

RESUMO

The neural basis of statistical learning as it occurs over time was explored with stimuli drawn from a natural language (Russian nouns). The input reflected the "rules" for marking categories of gendered nouns, without making participants explicitly aware of the nature of what they were to learn. Participants were scanned while listening to a series of gender-marked nouns during four sequential scans, and were tested for their learning immediately after each scan. Although participants were not told the nature of the learning task, they exhibited learning after their initial exposure to the stimuli. Independent component analysis of the brain data revealed five task-related sub-networks. Unlike prior statistical learning studies of word segmentation, this morphological learning task robustly activated the inferior frontal gyrus during the learning period. This region was represented in multiple independent components, suggesting it functions as a network hub for this type of learning. Moreover, the results suggest that subnetworks activated by statistical learning are driven by the nature of the input, rather than reflecting a general statistical learning system.

7.
Am J Disaster Med ; 10(4): 295-9, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-27149310

RESUMO

The Centers for Disease Control and Prevention (CDC) Quarantine Stations distribute select lifesaving drug products that are not commercially available or are in limited supply in the United States for emergency treatment of certain health conditions. Following a retrospective analysis of shipment records, the authors estimated an average of 6.66 hours saved per shipment when drug products were distributed from quarantine stations compared to a hypothetical centralized site from CDC headquarters in Atlanta, GA. This evaluation supports the continued use of a decentralized model which leverages CDC's regional presence and maximizes efficiency in the distribution of lifesaving drugs.


Assuntos
Centers for Disease Control and Prevention, U.S. , Emergências , Hospitais de Isolamento , Preparações Farmacêuticas/provisão & distribuição , Meios de Transporte/estatística & dados numéricos , Antimaláricos/provisão & distribuição , Artemisininas/provisão & distribuição , Artesunato , Antitoxina Botulínica , Antitoxina Diftérica , Georgia , Humanos , Fatores Imunológicos/provisão & distribuição , Estudos Retrospectivos , Fatores de Tempo , Tempo para o Tratamento , Estados Unidos
8.
J Emerg Manag ; 13(1): 19-23, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25779896

RESUMO

The Centers for Disease Control and Prevention (CDC) Quarantine Stations distribute select lifesaving drug products that are not commercially available or are in limited supply in the United States for emergency treatment of certain health conditions. Following a retrospective analysis of shipment records, the authors estimated an average of 6.66 hours saved per shipment when drug products were distributed from quarantine stations compared to a hypothetical centralized site from CDC headquarters in Atlanta, GA. This evaluation supports the continued use of a decentralized model which leverages CDC's regional presence and maximizes efficiency in the distribution of lifesaving drugs.


Assuntos
Centers for Disease Control and Prevention, U.S. , Emergências , Tratamento de Emergência/métodos , Sistemas de Medicação , Quarentena/métodos , Estoque Estratégico , Centers for Disease Control and Prevention, U.S./organização & administração , Centers for Disease Control and Prevention, U.S./estatística & dados numéricos , Controle de Formulários e Registros , Humanos , Sistemas de Medicação/organização & administração , Sistemas de Medicação/estatística & dados numéricos , Modelos Organizacionais , Avaliação de Programas e Projetos de Saúde , Estoque Estratégico/métodos , Estoque Estratégico/organização & administração , Fatores de Tempo , Meios de Transporte , Estados Unidos
9.
Wiley Interdiscip Rev Cogn Sci ; 4(5): 511-522, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26304243

RESUMO

Nonadjacent dependencies occur over one or more intervening units and require learners to track discontinuous sequential relationships. These discontinuous relationships are present at multiple levels in language (e.g., as seen in morphosyntactic dependencies and at the phonological level in vowel harmony). Experiments suggest that these dependencies are acquired using statistical learning mechanisms and that this learning is also affected by perceptual biases. Artificial and natural language studies have shown that infants are sensitive to these statistical regularities but there appear to be developmental constraints on learning. Developmental investigations have also examined how knowledge and processing of the intervening elements affect learning, and whether categories can be acquired using nonadjacent dependency information. WIREs Cogn Sci 2013, 4:511-522. doi: 10.1002/wcs.1244 CONFLICT OF INTEREST: The authors have declared no conflicts of interest for this article. For further resources related to this article, please visit the WIREs website.

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