Detalhe da pesquisa
1.
First Steps to Develop and Validate a CFPD Model in Order to Support the Design of Nose-to-Brain Delivered Biopharmaceuticals.
Pharm Res
; 33(6): 1337-50, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26887679
2.
Differential Regulation of Neurotrophic Factors During Pathogenic Tau-Aggregation in a Tau Transgenic Mouse Model for Alzheimer's Disease: A Protocol for Double-Labeling mRNA by In Situ Hybridization and Protein Epitopes by Immunohistochemistry.
Methods Mol Biol
; 2754: 361-385, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38512677
3.
Intranasal Nose-to-Brain Drug Delivery via the Olfactory Region in Mice: Two In-Depth Protocols for Region-Specific Intranasal Application of Antibodies and for Expression Analysis of Fc Receptors via In Situ Hybridization in the Nasal Mucosa.
Methods Mol Biol
; 2754: 387-410, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38512678
4.
Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?
Immun Ageing
; 10(1): 18, 2013 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23663286
5.
Fc-Engineered Therapeutic Antibodies: Recent Advances and Future Directions.
Pharmaceutics
; 15(10)2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896162
6.
Nogo-A antibody delivery through the olfactory mucosa mitigates experimental autoimmune encephalomyelitis in the mouse CNS.
Cell Death Discov
; 9(1): 290, 2023 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558696
7.
A Novel MATLAB®-Algorithm-Based Video Analysis to Quantitatively Determine Solution Creeping in Intact Pharmaceutical Glass Vials.
Eur J Pharm Biopharm
; 178: 117-130, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35961565
8.
Regulation of GDF-15, a distant TGF-ß superfamily member, in a mouse model of cerebral ischemia.
Cell Tissue Res
; 343(2): 399-409, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21128084
9.
Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration.
Antibodies (Basel)
; 10(4)2021 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939999
10.
Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System.
Front Pharmacol
; 12: 789780, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082672
11.
Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa.
Front Pharmacol
; 12: 732954, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34539414
12.
Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa.
Pharmaceutics
; 13(11)2021 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834319
13.
Impact of Glycosylation and Species Origin on the Uptake and Permeation of IgGs through the Nasal Airway Mucosa.
Pharmaceutics
; 12(11)2020 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33114132
14.
Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650.
Pharmaceutics
; 11(8)2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31374872
15.
Efficient Construction and Effective Screening of Synthetic Domain Antibody Libraries.
Methods Protoc
; 2(1)2019 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31164599
16.
Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa.
Pharmaceutics
; 10(3)2018 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30081536
17.
Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?
Pharmaceutics
; 10(3)2018 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30050027
18.
Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy.
Neuromolecular Med
; 9(4): 340-54, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17963048
19.
Editorial: Intranasal Drug Delivery: Challenges and Opportunities.
Front Pharmacol
; 13: 868986, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35308245
20.
A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery.
Int J Pharm
; 532(1): 537-546, 2017 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28917988