Detalhe da pesquisa
1.
Differential effects of OATP2B1 on statin accumulation and toxicity in a beta cell model.
Toxicol Mech Methods
; 34(2): 130-147, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771097
2.
In-vitro characterization of coding variants with predicted functional implications in the efflux transporter multidrug resistance protein 4 (MRP4, ABCC4).
Pharmacogenet Genomics
; 32(3): 111-116, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34693929
3.
Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C.
Liver Int
; 42(4): 796-808, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35107877
4.
Drug interactions and pharmacogenetic factors contribute to variation in apixaban concentration in atrial fibrillation patients in routine care.
J Thromb Thrombolysis
; 49(2): 294-303, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564018
5.
Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1.
Drug Metab Dispos
; 47(8): 832-842, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31123035
6.
Apixaban and Rosuvas--tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease.
Drug Metab Dispos
; 46(5): 485-492, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472495
7.
A novel NUDT15 variant identified in Caucasian TPMT wild type patients with inflammatory bowel disease and azathioprine-related myelotoxicity.
Pharmacogenet Genomics
; 32(1): 39-41, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34751173
8.
Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas.
Histochem Cell Biol
; 148(4): 345-357, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493059
9.
Genetic Determinants of Clozapine-Induced Metabolic Side Effects.
Can J Psychiatry
; 62(2): 138-149, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681143
10.
Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters.
Drug Metab Dispos
; 42(8): 1268-74, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24829289
11.
Cost-Effectiveness Analysis of Pharmacogenomics (PGx)-Based Warfarin, Apixaban, and Rivaroxaban Versus Standard Warfarin for the Management of Atrial Fibrillation in Ontario, Canada.
Pharmacoeconomics
; 42(1): 69-90, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596504
12.
Does prescribing apixaban or rivaroxaban versus warfarin for patients diagnosed with atrial fibrillation save health system costs? A multivalued treatment effects analysis.
Eur J Health Econ
; 25(3): 397-409, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37195343
13.
Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy.
Blood
; 118(11): 3163-71, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21725053
14.
Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response.
Eur Heart J
; 33(22): 2856-2464a, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22374717
15.
DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation.
Curr Oncol
; 30(1): 663-672, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36661700
16.
Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine-Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia.
Clin Pharmacol Ther
; 113(6): 1326-1336, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36932910
17.
Genotype-guided dosing of vitamin K antagonists.
N Engl J Med
; 370(18): 1761-2, 2014 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24785215
18.
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
Hepatology
; 54(2): 644-54, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21538436
19.
Human skeletal muscle drug transporters determine local exposure and toxicity of statins.
Circ Res
; 106(2): 297-306, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19940267
20.
Association of Sex With Stroke and Bleeding Risk of Apixaban and Rivaroxaban in Elderly Atrial Fibrillation Patients Using Propensity Score Weights.
CJC Open
; 4(1): 56-64, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072028