Detalhe da pesquisa
1.
Phase 2 study of dovitinib in patients with relapsed or refractory multiple myeloma with or without t(4;14) translocation.
Eur J Haematol
; 95(4): 316-24, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25402977
2.
Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors.
Invest New Drugs
; 32(1): 135-44, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589214
3.
Ceritinib plus Nivolumab in Patients with Advanced ALK-Rearranged Non-Small Cell Lung Cancer: Results of an Open-Label, Multicenter, Phase 1B Study.
J Thorac Oncol
; 15(3): 392-403, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31634667
4.
Preliminary evidence of disease response to the pan deacetylase inhibitor panobinostat (LBH589) in refractory Hodgkin Lymphoma.
Br J Haematol
; 147(1): 97-101, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19663825
5.
Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors.
Clin Cancer Res
; 14(20): 6663-73, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18927309
6.
A drug-drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 81(1): 73-80, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101463
7.
Assessment of drug-drug interaction potential between ceritinib and proton pump inhibitors in healthy subjects and in patients with ALK-positive non-small cell lung cancer.
Cancer Chemother Pharmacol
; 79(6): 1119-1128, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28424965
8.
ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).
J Thorac Oncol
; 12(9): 1357-1367, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729021
9.
Effects of meal type on the oral bioavailability of the ALK inhibitor ceritinib in healthy adult subjects.
J Clin Pharmacol
; 56(5): 559-66, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272586
10.
Randomized phase 1 crossover study assessing the bioequivalence of capsule and tablet formulations of dovitinib (TKI258) in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 78(5): 921-927, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681579
11.
A randomized, crossover phase 1 study to assess the effects of formulation (capsule vs tablet) and meal consumption on the bioavailability of dovitinib (TKI258).
Cancer Chemother Pharmacol
; 75(4): 729-37, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25648347
12.
The effect of formulation and food consumption on the bioavailability of dovitinib (TKI258) in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 74(4): 867-74, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193431
13.
The deacetylase inhibitor LAQ824 induces notch signalling in haematopoietic progenitor cells.
Leuk Res
; 35(1): 119-25, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20674020
14.
Vaccines and hurricanes don't mix.
Paediatr Child Health
; 9(7): 453-6, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19657407