Detalhe da pesquisa
1.
Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities.
Bioorg Med Chem Lett
; 86: 129258, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972793
2.
In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors.
Int J Mol Sci
; 23(7)2022 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409325
3.
Network pharmacology of triptolide in cancer cells: implications for transcription factor binding.
Invest New Drugs
; 39(6): 1523-1537, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213719
4.
A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy.
Invest New Drugs
; 39(4): 914-927, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33492639
5.
Cytotoxic Bufadienolides from the Leaves of Melianthus major.
J Nat Prod
; 83(7): 2122-2128, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663024
6.
Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa.
Bioorg Chem
; 102: 104102, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32721779
7.
Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System.
Molecules
; 25(19)2020 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998355
8.
Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease.
Pharmacol Res
; 129: 262-273, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29179999
9.
Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius.
Org Biomol Chem
; 16(9): 1581-1590, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443340
10.
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin.
Bioorg Med Chem
; 26(12): 3610-3618, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29887512
11.
Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities.
J Nat Prod
; 81(4): 918-933, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29560715
12.
Total Synthesis and Biological Investigation of (-)-Artemisinin: The Antimalarial Activity of Artemisinin Is not Stereospecific.
Angew Chem Int Ed Engl
; 57(27): 8293-8296, 2018 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29723442
13.
Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D.
Bioorg Med Chem
; 25(22): 6137-6148, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233677
14.
Synthesis and cytotoxic activity of new artemisinin hybrid molecules against human leukemia cells.
Bioorg Med Chem
; 25(13): 3357-3367, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28456567
15.
Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines.
J Nat Prod
; 80(2): 443-458, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28121440
16.
Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation.
Mar Drugs
; 15(3)2017 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273803
17.
Pharmacogenomics of Scopoletin in Tumor Cells.
Molecules
; 21(4): 496, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27092478
18.
Identification of cellular and molecular factors determining the response of cancer cells to six ergot alkaloids.
Invest New Drugs
; 33(1): 32-44, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342140
19.
Molecular determinants of the response of cancer cells towards geldanamycin and its derivatives.
Chem Biol Interact
; 383: 110677, 2023 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586545
20.
Construction of recombinant E. coli Nissle 1917 (EcN) strains for the expression and secretion of defensins.
Int J Med Microbiol
; 302(6): 276-87, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22748509