Detalhe da pesquisa
1.
A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.
J Virol
; 86(11): 6189-96, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22457527
2.
Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans.
Genes Cells
; 16(11): 1071-80, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22023369
3.
The N-linked oligosaccharide at Fc gamma RIIIa Asn-45: an inhibitory element for high Fc gamma RIIIa binding affinity to IgG glycoforms lacking core fucosylation.
Glycobiology
; 19(2): 126-34, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18952826
4.
Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors.
PLoS One
; 10(10): e0140120, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26444434
5.
Nonfucosylated rituximab potentiates human neutrophil phagocytosis through its high binding for FcgammaRIIIb and MHC class II expression on the phagocytotic neutrophils.
Exp Hematol
; 37(3): 309-21, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19218011