[The characteristics of perceptive learning and memory in psychopathological states]. / Osobennosti pertseptivnogo obucheniia i pamiati pri psikhopatologicheskikh sostoianiiakh.

Dynamics is studied of visual images recognition in patients with schizophrenia under the influence of small doses of ionizing radiation used with therapeutic purpose. Functional state of the brain is evaluated by amplitude-temporal parameters of visual and auditory EPs. After conducted therapy no changes in responses to light flashes are found, and in auditory EPs in a part (the first group) of patients there is an increase of the component N1 amplitude in the frontal area. The same group is characterized by lower parameters of visual images recognition. Conclusion is made about the presence of non-specific changes of visual gnosis in patients with schizophrenia and about involvement of the associative frontal structures in pathologic process. Possible mechanisms of disturbance of the perceptive learning and memory processes in schizophrenia are discussed.

[Status of microhemodynamics and features of capillary permeability in schizophrenia]. / Sostoianie mikrogemodinamiki i osobennosti pronitsaemosti kapilliarov pri shizofrenii.

Using a complex of physiological methods developed by the author the initial state of bilateral permeability of the capillaries, the supply of tissues with blood through the capillaries, and the character of changes of those parameters in the conditions of the adaptational activity of microcirculation in schizophrenic patients were studied. It has been found that three types of microcirculation disturbances leading to tissue hypoxia can be distinguished in schizophrenia depending on the process type and stage. The types of the capillary permeability disturbances in various forms of the schizophrenic process are described.

[Dynamic diagnosis of psychopathies]. / O dinamicheskoi diagnostike psikhopatii.

It has been discovered that in persons aged 18-20 years, the establishment of psychopathy is not always completed. Later many of them get steadily compensated and do not seek treatment. In view of this circumstance it is suggested that for this particular age dynamic diagnosis of psychopathies may be employed. It is based on the hypothesis of ontogenetic counterbalancing of early-age associated personality disharmony, of the development with age of the mechanisms of psychological sanogenesis and defence, and enhancement of the adaptive social structure of the personality conduct.

[Recollections and ideas in tobacco dependence]. / Osobennosti techeniia vospominanii i predstavlenii pri tabachnoi zavisimosti.

++Clinico-psychopathological and patho-psychological methods were employed to study statically and over time the main types of reproducing recollections, ideas and correlations to the motivation and formation of tobacco dependence in 480 smokers and non-smokers. Three basic types of reproducing recollections and ideas, namely mental, image-bearing, and mental and image-bearing were distinguished. The main space and time constitutional forms of the types of the development of recollections and ideas are presented. In patients with tobacco dependence, the characteristic features of the explored types of recollections and ideas are viewed as one of the risk factors of the onset of tobacco dependence. The data are presented about their implication in the formation of pathological craving for tobacco smoking.

[Characteristics of psychopathology of tobacco dependence]. / Osobennosti psikhopatologii tabachnoi zavisimosti.

Overall 320 patients were examined for the clinical picture of tobacco-smoking. The whole clinical diversity of tobacco-smoking is reduced to the common system in which two independently existing variants of tobacco-smoking are distinguished: in the form of a tobacco-smoking habit and tobacco dependence. Tobacco dependence is viewed as a current psychopathological process having a localized and partial nature. A psychopathological delineation of tobacco dependence is provided. Three forms of tobacco dependence are described at the syndromal level. It is emphasized that tobacco dependence does not refer to toxicomania or narcomania in terms of its clinical manifestations, occupying an intermediate place in psychopathology, namely between mental health, one the one hand, and borderline neuropsychic disorders, on the other one.

[The pathogenetic, clinical and treatment problems of the mental disorders in brain trauma]. / Voprosy patogeneza, kliniki i lecheniia psikhicheskikh narushenii pri travme golovnogo mozga.

Authors examine the questions of pathogenesis and clinic of mental disorders caused by cerebrum traumata, as well as the peculiarities of its diagnosis and treatment. There is a principle scheme of systematized post-aggressive reaction after cerebrum injury which emphasises the necessity to study the pathophysiological process from the point of view of norm in pathology, development of protective mechanisms and individual peculiarities (sanagenetical approach). The structural and syndromological method is proposed to appreciate mental disorders and distinguish the variants of psychopathological syndromes. Therapy aspects of some mental disorders are interpreted from the point of view of sanagenetical position.

[Primary and secondary resistance to nicotine replacement therapy in tobacco dependent patients].

The terms of primary and secondary resistance to nicotine replacement therapy in tobacco dependent patients are defined. It is shown that treatment resistance is a result of a constellation of special clinical features of tobacco dependence, tolerance to nicotine, personality traits of the patients, family history of smoking, comorbid affective disorders and somatic diseases.